Journal Article

My46: a Web-based tool for self-guided management of genomic test results in research and clinical settings

Yu, Joon-Ho, Crouch, Julia M., Futral, Brett T., Shankar, Aditi G., Tabor, Holly K., Bamshad, Michael J., Miller, Damon A., Jamal, Seema M., Dent, Karin M., Anderson, Nick

2017

Overview

A major challenge to implementing precision medicine is the need for an efficient and cost-effective strategy for returning individual genomic test results that is easily scalable and can be incorporated into multiple models of clinical practice. My46 is a Web-based tool for managing the return of genetic results that was designed and developed to support a wide range of approaches to disclosing results, ranging from traditional face-to-face disclosure to self-guided models. My46 has five key functions: set and modify results-return preferences, return results, educate, manage the return of results, and assess the return of results. These key functions are supported by six distinct modules and a suite of features that enhance the user experience, ease site navigation, facilitate knowledge sharing, and enable results-return tracking. My46 is a potentially effective solution for returning results and supports current trends toward shared decision making between patients and providers and patient-driven health management. Genet Med19 4, 467–475.

• Publisher: Elsevier Inc,Nature Publishing Group US,Elsevier Limited
• Subject: 631/114 / 631/1647/514 / 692/700/228/2050/1512 / Biomedical Research / Biomedicine / Computational Biology - methods / Decision Making / exome sequencing / genome sequencing / Genomics / Human Genetics / Humans / incidental / Internet / Laboratory Medicine / Medical Informatics / Patient Access to Records / Precision Medicine / results return / secondary results / special-article