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Prophylaxis with Single-Dose Doxycycline for the Prevention of Lyme Disease after an Ixodes scapularis Tick Bite
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Prophylaxis with Single-Dose Doxycycline for the Prevention of Lyme Disease after an Ixodes scapularis Tick Bite
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Journal Article
Prophylaxis with Single-Dose Doxycycline for the Prevention of Lyme Disease after an Ixodes scapularis Tick Bite
2001
Overview
This large trial shows the efficacy of a single, prophylactic dose of doxycycline to prevent Lyme disease.
Lyme disease is transmitted by the bite of an
Ixodes scapularis
tick and is the most common vector-borne disease in the United States.
1
This infection may be prevented by vaccination.
2
,
3
However, the vaccine's general acceptance is likely to be limited by its cost (a cost to the pharmacist of $61.25 per dose) and the need for multiple doses to achieve and maintain protection.
2
,
3
In addition, the vaccine is less than 100 percent effective and is currently approved only for persons 15 to 70 years of age.
3
Antimicrobial prophylaxis for persons with
I. scapularis
tick bites may be a . . .
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Aged
/ Animals
/ Anti-Bacterial Agents - administration & dosage
/ Anti-Bacterial Agents - adverse effects
/ Antibiotics. Antiinfectious agents. Antiparasitic agents
/ Biological and medical sciences
/ Borrelia burgdorferi Group - isolation & purification
/ Child
/ Doxycycline - administration & dosage
/ Doxycycline - adverse effects
/ Erythema Chronicum Migrans - prevention & control
/ Female
/ Humans
/ Ixodes - growth & development
/ Ixodidae
/ Lyme Disease - prevention & control
/ Male
/ Nymph
