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Use of a Continuous-Flow Device in Patients Awaiting Heart Transplantation
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Use of a Continuous-Flow Device in Patients Awaiting Heart Transplantation
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Journal Article
Use of a Continuous-Flow Device in Patients Awaiting Heart Transplantation
2007
Overview
A series of 133 patients with severe heart failure underwent implantation of a continuous-flow left ventricular assist device. At 6 months, 75% of the patients had undergone heart transplantation, had cardiac recovery with device explantation, or continued to receive device support without any contraindication to subsequent transplantation. Important adverse events included postoperative bleeding, stroke, heart failure, and drive-line infection.
A series of 133 patients with severe heart failure underwent implantation of a continuous-flow left ventricular assist device. At 6 months, 75% of the patients had undergone heart transplantation, had cardiac recovery, or continued to receive device support without any contraindication to subsequent transplantation.
Therapy with a left ventricular assist device is an established form of treatment for patients with refractory heart failure.
1
In the United States, most patients undergoing implantation of such a device as a bridge to heart transplantation have received support from pulsatile volume-displacement devices that fill with and eject blood in a cyclic fashion that is analogous to the systole and diastole of the native heart.
2
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7
These devices provide excellent hemodynamic support and improve survival but have substantial constraints, including the need for extensive surgical dissection, the requirement that the recipient have a large body habitus, the presence of . . .
Publisher
Massachusetts Medical Society
Subject
