Asset Details
Do you wish to reserve the book?
PCR-based detection of gene transfer vectors: application to gene doping surveillance
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
PCR-based detection of gene transfer vectors: application to gene doping surveillance
Do you wish to request the book?
PCR-based detection of gene transfer vectors: application to gene doping surveillance
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
PCR-based detection of gene transfer vectors: application to gene doping surveillance
2013
Overview
Athletes who illicitly use drugs to enhance their athletic performance are at risk of being banned from sports competitions. Consequently, some athletes may seek new doping methods that they expect to be capable of circumventing detection. With advances in gene transfer vector design and therapeutic gene transfer, and demonstrations of safety and therapeutic benefit in humans, there is an increased probability of the pursuit of gene doping by athletes. In anticipation of the potential for gene doping, assays have been established to directly detect complementary DNA of genes that are top candidates for use in doping, as well as vector control elements. The development of molecular assays that are capable of exposing gene doping in sports can serve as a deterrent and may also identify athletes who have illicitly used gene transfer for performance enhancement. PCR-based methods to detect foreign DNA with high reliability, sensitivity, and specificity include TaqMan real-time PCR, nested PCR, and internal threshold control PCR.
Publisher
Springer Berlin Heidelberg,Springer,Springer Nature B.V
Subject
/ Assaying
/ Athletes
/ Characterization and Evaluation of Materials
/ Chemistry and Materials Science
/ DNA
/ Doping
/ Doping in Sports - prevention & control
/ drugs
/ Genes
/ Genomes
/ Humans
/ Monitoring/Environmental Analysis
/ Performance-Enhancing Substances - analysis
/ Polymerase Chain Reaction - methods
/ quantitative polymerase chain reaction
/ Review
/ risk
/ sports
/ Urine
