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A Simple Near‐Infrared Fluorescent Probe for the Detection of Peroxynitrite
by
He, Xiao‐Peng
, Han, Hai‐Hao
, Groleau, Robin R.
, Bull, Steven D.
, Wu, Luling
, Wannalerse, Boontana
, Sedgwick, Adam C.
, James, Tony D.
, Tosuwan, Paramabhorn
, Tian, Xue
, Wang, Jie
in
Biocompatibility
/ boronate
/ Chemical synthesis
/ Chromatography
/ Communication
/ Communications
/ fluorescence
/ Fluorescent indicators
/ Hydrogen peroxide
/ near-infrared
/ peroxynitrite
/ probe
/ Sensors
2019
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A Simple Near‐Infrared Fluorescent Probe for the Detection of Peroxynitrite
by
He, Xiao‐Peng
, Han, Hai‐Hao
, Groleau, Robin R.
, Bull, Steven D.
, Wu, Luling
, Wannalerse, Boontana
, Sedgwick, Adam C.
, James, Tony D.
, Tosuwan, Paramabhorn
, Tian, Xue
, Wang, Jie
in
Biocompatibility
/ boronate
/ Chemical synthesis
/ Chromatography
/ Communication
/ Communications
/ fluorescence
/ Fluorescent indicators
/ Hydrogen peroxide
/ near-infrared
/ peroxynitrite
/ probe
/ Sensors
2019
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A Simple Near‐Infrared Fluorescent Probe for the Detection of Peroxynitrite
by
He, Xiao‐Peng
, Han, Hai‐Hao
, Groleau, Robin R.
, Bull, Steven D.
, Wu, Luling
, Wannalerse, Boontana
, Sedgwick, Adam C.
, James, Tony D.
, Tosuwan, Paramabhorn
, Tian, Xue
, Wang, Jie
in
Biocompatibility
/ boronate
/ Chemical synthesis
/ Chromatography
/ Communication
/ Communications
/ fluorescence
/ Fluorescent indicators
/ Hydrogen peroxide
/ near-infrared
/ peroxynitrite
/ probe
/ Sensors
2019
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A Simple Near‐Infrared Fluorescent Probe for the Detection of Peroxynitrite
Journal Article
A Simple Near‐Infrared Fluorescent Probe for the Detection of Peroxynitrite
2019
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Overview
Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM‐Bpin for the detection of peroxynitrite (ONOO−). DCM‐Bpin exhibits selective fluorescence off‐on response for ONOO− over other reactive oxygen species, including H2O2. Moreover, DCM‐Bpin is biocompatible and has been used to visualize exogenous ONOO− in HeLa cells.
Turn on the light: A 50‐fold “turn‐on” fluorescence response at 667 nm was observed for DCM‐Bpin upon the addition of ONOO− (0–27 equiv.) using an excitation wavelength of 560 nm.
Publisher
John Wiley & Sons, Inc,John Wiley and Sons Inc,Wiley-VCH
Subject
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