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The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications
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Journal Article
The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications
2016
Overview
Pinocembrin is a natural flavonoid compound extracted from honey, propolis, ginger roots, wild marjoram, and other plants. In preclinical studies, it has shown anti-inflammatory and neuroprotective effects as well as the ability to reduce reactive oxygen species, protect the blood-brain barrier, modulate mitochondrial function, and regulate apoptosis. Considering these pharmaceutical characteristics, pinocembrin has potential as a drug to treat ischemic stroke and other clinical conditions. In this review, we summarize its pharmacologic characteristics and discuss its mechanisms of action and potential therapeutic applications.
Publisher
Springer US,Springer Nature B.V
