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Effectiveness of transurethral resection combined with sapylin for bladder perfusion in glandular cystitis
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Effectiveness of transurethral resection combined with sapylin for bladder perfusion in glandular cystitis
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Journal Article
Effectiveness of transurethral resection combined with sapylin for bladder perfusion in glandular cystitis
2025
Overview
This study explored the impact of transurethral resection plus sapylin for bladder perfusion in treating glandular cystitis. One hundred and twenty-eight cases of glandular cystitis who accepted therapy in Renmin Hospital of Wuhan University, Wuhan, China from September 2018 to September 2022 were chosen and randomly separated into a control group (CG, n=64) and a research group (RG, n=64). The CG received transurethral resection. In contrast, the RG received sapylin infusion chemotherapy in addition to transurethral resection. The clinical efficacy, urination function, levels of inflammatory factors, quality of life along with adverse reactions in the two groups was compared. Relative to the CG, the RG showed higher total treatment effectiveness rate, better improvements of urination function and inflammation, higher quality of life scores, and lower occurrence of adverse reactions. We conclude that transurethral resection combined with sapylin for bladder perfusion has higher effectiveness in treatment of glandular cystitis when compared to transurethral resection alone.
Cette étude a exploré l'impact de la résection transurétrale associée à la sapyline pour la perfusion vésicale dans le traitement de la cystite glandulaire. Cent vingt-huit cas de cystite glandulaire, traités à l'hôpital Renmin de l'université de Wuhan, en Chine, entre septembre 2018 et septembre 2022, ont été sélectionnés et répartis aléatoirement en un groupe témoin (GC, n = 64) et un groupe de recherche (RG, n = 64). Le GC a bénéficié d'une résection transurétrale. À l'inverse, le RG a reçu une chimiothérapie par perfusion de sapyline en plus de la résection transurétrale. L'efficacité clinique, la fonction urinaire, les niveaux de facteurs inflammatoires, la qualité de vie et les effets indésirables des deux groupes ont été comparés. Par rapport au GC, le RG a montré un taux d'efficacité thérapeutique global plus élevé, une meilleure amélioration de la fonction urinaire et de l'inflammation, des scores de qualité de vie plus élevés et une incidence plus faible d'effets indésirables. Nous concluons que la résection transurétrale associée à la sapyline pour la perfusion vésicale est plus efficace dans le traitement de la cystite glandulaire que la résection transurétrale seule.
Publisher
Women’s Health and Action Research Centre,Women's Health and Action Research Centre (WHARC),Women's Health and Action Research Centre
