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The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients
by
Stoppe, Christian
, Klek, Stanislaw
, Patel, Jayshil J.
, Calder, Philip C.
, Wischmeyer, Paul E.
, Martindale, Robert G.
in
Acute Care Surgery
/ Biomarkers
/ Brief Report
/ Clinical outcomes
/ Critical care
/ Critical Care - methods
/ Critical Care Medicine
/ Critical Illness - therapy
/ Emergency Medicine
/ Evidence-based medicine
/ Fat Emulsions, Intravenous - administration & dosage
/ Fat Emulsions, Intravenous - therapeutic use
/ Fatty acids
/ Fatty Acids, Omega-3 - administration & dosage
/ Fatty Acids, Omega-3 - therapeutic use
/ Fish oils
/ Fish Oils - administration & dosage
/ Fish Oils - therapeutic use
/ Homeostasis
/ Hospitals
/ Humans
/ Illnesses
/ Inflammation
/ Intensive
/ Lipids
/ Medicine
/ Medicine & Public Health
/ Meta-analysis
/ Metabolism
/ Mortality
/ Nutrition
/ Omega-3 fatty acids
/ Oxidative stress
/ Parenteral nutrition
/ Parenteral Nutrition - methods
/ Parenteral Nutrition - standards
/ Patients
/ Polyunsaturated fatty acids
/ Proteins
/ Soybeans
/ Unsaturated fatty acids
/ Vegetable oils
2024
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The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients
by
Stoppe, Christian
, Klek, Stanislaw
, Patel, Jayshil J.
, Calder, Philip C.
, Wischmeyer, Paul E.
, Martindale, Robert G.
in
Acute Care Surgery
/ Biomarkers
/ Brief Report
/ Clinical outcomes
/ Critical care
/ Critical Care - methods
/ Critical Care Medicine
/ Critical Illness - therapy
/ Emergency Medicine
/ Evidence-based medicine
/ Fat Emulsions, Intravenous - administration & dosage
/ Fat Emulsions, Intravenous - therapeutic use
/ Fatty acids
/ Fatty Acids, Omega-3 - administration & dosage
/ Fatty Acids, Omega-3 - therapeutic use
/ Fish oils
/ Fish Oils - administration & dosage
/ Fish Oils - therapeutic use
/ Homeostasis
/ Hospitals
/ Humans
/ Illnesses
/ Inflammation
/ Intensive
/ Lipids
/ Medicine
/ Medicine & Public Health
/ Meta-analysis
/ Metabolism
/ Mortality
/ Nutrition
/ Omega-3 fatty acids
/ Oxidative stress
/ Parenteral nutrition
/ Parenteral Nutrition - methods
/ Parenteral Nutrition - standards
/ Patients
/ Polyunsaturated fatty acids
/ Proteins
/ Soybeans
/ Unsaturated fatty acids
/ Vegetable oils
2024
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The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients
by
Stoppe, Christian
, Klek, Stanislaw
, Patel, Jayshil J.
, Calder, Philip C.
, Wischmeyer, Paul E.
, Martindale, Robert G.
in
Acute Care Surgery
/ Biomarkers
/ Brief Report
/ Clinical outcomes
/ Critical care
/ Critical Care - methods
/ Critical Care Medicine
/ Critical Illness - therapy
/ Emergency Medicine
/ Evidence-based medicine
/ Fat Emulsions, Intravenous - administration & dosage
/ Fat Emulsions, Intravenous - therapeutic use
/ Fatty acids
/ Fatty Acids, Omega-3 - administration & dosage
/ Fatty Acids, Omega-3 - therapeutic use
/ Fish oils
/ Fish Oils - administration & dosage
/ Fish Oils - therapeutic use
/ Homeostasis
/ Hospitals
/ Humans
/ Illnesses
/ Inflammation
/ Intensive
/ Lipids
/ Medicine
/ Medicine & Public Health
/ Meta-analysis
/ Metabolism
/ Mortality
/ Nutrition
/ Omega-3 fatty acids
/ Oxidative stress
/ Parenteral nutrition
/ Parenteral Nutrition - methods
/ Parenteral Nutrition - standards
/ Patients
/ Polyunsaturated fatty acids
/ Proteins
/ Soybeans
/ Unsaturated fatty acids
/ Vegetable oils
2024
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The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients
Journal Article
The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients
2024
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Overview
In critical illness the regulation of inflammation and oxidative stress can improve patient outcomes, and thus omega-3 polyunsaturated fatty acids (PUFAs) have been used as part of parenteral nutrition (PN) owing to their potential anti-inflammatory effects. The international lipids in PN Summit, encompassed discussions and the production of consensus guidelines concerning PN intravenous lipid emulsion (ILE) use in critical care. The Lipid Summit participants agreed that the inclusion of fish oil in ILEs is associated with meaningful clinical benefits without signals of harm, based on a strong biological rationale and current clinical evidence. Decisions concerning ILE choice should be made based on current evidence, thus addressing clinical requirements for guidance, particularly as further definitive evidence seems unlikely to occur. In addition, a future of individualized ICU care is envisioned, yielding better clinical outcomes. This approach will require the greater use of intelligent study designs incorporating the use of biomarkers of omega-3 derivatives, inflammatory-resolving processes, and/or muscle protein breakdown.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V
Subject
/ Fat Emulsions, Intravenous - administration & dosage
/ Fat Emulsions, Intravenous - therapeutic use
/ Fatty Acids, Omega-3 - administration & dosage
/ Fatty Acids, Omega-3 - therapeutic use
/ Fish Oils - administration & dosage
/ Humans
/ Lipids
/ Medicine
/ Parenteral Nutrition - methods
/ Parenteral Nutrition - standards
/ Patients
/ Proteins
/ Soybeans
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