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Maternal exercise and its beneficial effects on glucose metabolism in offspring
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Journal Article
Maternal exercise and its beneficial effects on glucose metabolism in offspring
2020
Overview
It shows that detrimental exposures and conditions in mothers can lead to the development of obesity and type 2 diabetes in offspring. This can lead to a vicious cycle of metabolic dysfunction, where rising rates of obesity, pre-diabetes, and diabetes in individuals of reproductive age, propagating risks to subsequent generations. It is well established that regular exercise has important health benefits for people with obesity and type 2 diabetes. Recently, increasing studies aim to examine the effects of maternal exercise on metabolic health in offspring. This review aims to demonstrate the evidence linking maternal exercise during critical periods of development and its implications for glucose metabolism in offspring, including intervention timing, sexual dimorphism, different exercise type, and intensity. Then we further examine the potential role of epigenetic modifications in this process.
Publisher
The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license,Lippincott Williams & Wilkins Ovid Technologies,Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Diabetes Research Center of Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China,Wolters Kluwer Health,Wolters Kluwer
