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Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest

by Grejs, Anders M. , Bäcklund, Minna , Walsham, James , Taccone, Fabio S. , Monahan, Sinéad , Chia, Yew Woon , Flaa, Arnljot , Iten, Manuela , Arabi, Yaseen , Knight, David , Horn, Janneke , Annoni, Filippo , Düring, Joachim P. , Lilja, Gisela , Fahey, Ciara , Ghosh, Angajendra , Tlayjeh, Haytham , Olasveengen, Theresa , Markota, Andrej , Dankiewicz, Josef , Capellier, Gilles , Christensen, Steffen , Ainscough, Kate , Tiainen, Marjaana , Bailey, Michael J. , McGuigan, Peter J. , Thomas, Matthew , Pogson, David , Bellomo, Rinaldo , Hodgson, Carol , Cronberg, Tobias , McGuinness, Shay , Hænggi, Matthias , Trapani, Tony , Bernard, Stephen , Ady, Bridget , Chen, Yan , Andersen, Geir Ø. , Peck, Leah , Deane, Adam , Stub, Dion , Nichol, Alistair D. , Paul, Eldho , Parke, Rachael L. , Eastwood, Glenn , Lesona, Eden , Bewley, Jeremy , Hunt, Anna , Nielsen, Niklas , Skrifvars, Markus B. , Qvigstad, Eirik , Cole, Jade , Munk-Andersen, Heidi , Kirkegaard, Hans , Landoni, Giovanni , Granfeldt, Asger , Wise, Matt P. , Sweet, Katie , Hilty, Matthias P. , Levis, Anja , Kutsogiannis, Demetrios , Svenšek, Franc , Archer, John

in Adult / Anestesi och intensivvård / Anesthesia / Anesthesiology and Intensive Care / Binomial distribution / Blood flow / Blood pressure / Brain Death / Carbon dioxide / Carbon Dioxide - blood / Cardiac Arrest / Cardiology / Cardiology General / Cardiopulmonary Resuscitation / Cerebral blood flow / Clinical Medicine / Clinical Medicine General / Coma / Coma - blood / Coma - etiology / Confidence intervals / Consent / Critical Care / Death / Emergency Medicine / Emergency Medicine General / Heart / Hospital-Based Clinical Medicine / Hospitalization / Humans / Hypercapnia / Hypercapnia - blood / Hypercapnia - etiology / Hypothermia / Klinisk medicin / Medical and Health Sciences / Medical prognosis / Medical research / Medicin och hälsovetenskap / Neurology / Neurosurgery / Neurosurgery General / Out-of-Hospital Cardiac Arrest - blood / Out-of-Hospital Cardiac Arrest - complications / Out-of-Hospital Cardiac Arrest - therapy / Patients / Physiology / Pulmonary / Quality of life / Statistical analysis / Survival analysis

2023

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2023

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2023

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Journal Article

Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest

Grejs, Anders M.,

Bäcklund, Minna,

Walsham, James,

Taccone, Fabio S.,

Monahan, Sinéad,

Chia, Yew Woon,

Flaa, Arnljot,

Iten, Manuela,

Arabi, Yaseen,

Knight, David,

Horn, Janneke,

Annoni, Filippo,

Düring, Joachim P.,

Lilja, Gisela,

Fahey, Ciara,

Ghosh, Angajendra,

Tlayjeh, Haytham,

Olasveengen, Theresa,

Markota, Andrej,

Dankiewicz, Josef,

Capellier, Gilles,

Christensen, Steffen,

Ainscough, Kate,

Tiainen, Marjaana,

Bailey, Michael J.,

McGuigan, Peter J.,

Thomas, Matthew,

Pogson, David,

Bellomo, Rinaldo,

Hodgson, Carol,

Cronberg, Tobias,

McGuinness, Shay,

Hænggi, Matthias,

Trapani, Tony,

Bernard, Stephen,

Ady, Bridget,

Chen, Yan,

Andersen, Geir Ø.,

Peck, Leah,

Deane, Adam,

Stub, Dion,

Nichol, Alistair D.,

Paul, Eldho,

Parke, Rachael L.,

Eastwood, Glenn,

Lesona, Eden,

Bewley, Jeremy,

Hunt, Anna,

Nielsen, Niklas,

Skrifvars, Markus B.,

Qvigstad, Eirik,

Cole, Jade,

Munk-Andersen, Heidi,

Kirkegaard, Hans,

Landoni, Giovanni,

Granfeldt, Asger,

Wise, Matt P.,

Sweet, Katie,

Hilty, Matthias P.,

Levis, Anja,

Kutsogiannis, Demetrios,

Svenšek, Franc,

Archer, John

2023

Overview

In a trial involving patients with coma after out-of-hospital cardiac arrest, a strategy targeting mild hypercapnia for 24 hours did not improve neurologic outcomes at 6 months as compared with targeted normocapnia.

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Publisher

Massachusetts Medical Society

Subject

Adult

/ Anestesi och intensivvård

/ Anesthesia

/ Anesthesiology and Intensive Care

/ Binomial distribution

/ Blood flow

/ Blood pressure