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Calcium and vitamin D in obesity
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Journal Article
Calcium and vitamin D in obesity
2012
Overview
New and more effective nutritional measures are urgently needed for the prevention of obesity. The role of Ca and vitamin D in obesity has been recently implicated. Low Ca intake and low vitamin D status have been linked with an increased risk of obesity in epidemiological studies; however, clinical intervention trials designed to test this association have produced controversial results. The suggested anti-obesity mechanisms of Ca and vitamin D include the regulation of adipocyte death (apoptosis), adipogenesis and lipid metabolism. Dietary Ca has been also shown to increase faecal fat excretion. The potential role of Ca and vitamin D in shifting energy balance towards a more negative state is an area of considerable interest. Ultimately, a review of recent research findings does not allow the reaching of a definitive conclusion that increasing Ca intake and rising vitamin D status will influence fat mass and body weight or decrease the risk of obesity and overweight.
Publisher
Cambridge University Press
Subject
/ Adipose Tissue - drug effects
/ Biological and medical sciences
/ Body Composition - drug effects
/ Calcium
/ Calcium, Dietary - pharmacology
/ Calcium, Dietary - therapeutic use
/ death
/ Diet
/ Energy Metabolism - drug effects
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Micronutrients - pharmacology
/ Micronutrients - therapeutic use
/ Obesity
/ Obesity - prevention & control
/ risk
/ Vertebrates: anatomy and physiology, studies on body, several organs or systems
