Journal Article

Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review

Lei, Dan, Wang, Shun, Peng, Chunxian, Chen, Xiguo, Chen, Meiqin

2025

Overview

Hepatic angiosarcoma is an extremely rare, uncontrollable tumor with strong invasion, high mortality rate, and extremely poor prognosis. There is first report on hepatic angiosarcoma accompanied by eosinophilia. A woman with a chief complaint of poor appetite for about 3 months presented to a local hospital with a liver mass. Laboratory examination revealed a significant increase in eosinophils count was 9.58% in the serum. Abdominal MRI revealed multiple focal high-density lesions in the liver and spleen, and cranial MRI revealed multiple high-density shadows in the skull. Laparoscopic biopsy revealed a hepatic angiosarcoma and targeted treatment with Anlotinib was performed. Two months later, the patient died of splenic rupture and bleeding. Hepatic angiosarcoma often has no specific clinical manifestations, and we found that this case can lead to an increase in eosinophils, which is worth the attention of clinical physicians.

• Publisher: Dove Medical Press Limited,Taylor & Francis Ltd,Dove Press,Dove,Dove Medical Press
• Subject: Abdomen / Angiosarcoma / Biomarkers / Biopsy / Case Report / Case reports / Chemotherapy / diagnosis / Eosinophilia / hepatic angiosarcoma / hepatic angiosarcoma；eosinophilia；prognosis；diagnosis；case report / Inflammatory diseases / Laparoscopy / Liver / Magnetic resonance imaging / Medical prognosis / Metastasis / Mortality / Pathology / Patients / Prognosis / Sarcoma / Spleen / Tumors / Ultrasonic imaging