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Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

by Thompson, Vivian P , Holman, Rury R , Ramachandran, Ambady , Maggioni, Aldo P , Chan, Juliana C , Poulter, Neil , Hernandez, Adrian F , Öhman, Peter , Mentz, Robert J , Gustavson, Stephanie M , Iqbal, Nayyar , Lokhnygina, Yuliya , Buse, John B , Marso, Steven P , Bethel, M. Angelyn , Pagidipati, Neha J , Zinman, Bernard , Choi, Jasmine

in Aged / Amylin / Antidiabetics / Cardiovascular disease / Cardiovascular Diseases - complications / Cardiovascular Diseases - epidemiology / Cardiovascular Diseases - mortality / Cardiovascular Diseases - prevention & control / Cerebral infarction / Diabetes / Diabetes mellitus / Diabetes Mellitus, Type 2 - blood / Diabetes Mellitus, Type 2 - complications / Diabetes Mellitus, Type 2 - drug therapy / Double-Blind Method / Drug Administration Schedule / Drug therapy / Endocrinology / Exenatide / Female / Health risk assessment / Heart diseases / Humans / Hypoglycemic Agents - administration & dosage / Hypoglycemic Agents - adverse effects / Incidence / Injections, Subcutaneous / Kaplan-Meier Estimate / Least-Squares Analysis / Male / Middle Aged / Myocardial infarction / Pancreatic cancer / Pancreatic carcinoma / Pancreatitis / Patients / Peptides - administration & dosage / Peptides - adverse effects / Pharmaceuticals / Side effects / Thyroid cancer / Thyroid carcinoma / Venoms - administration & dosage / Venoms - adverse effects

2017

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Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

2017

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Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

2017

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Journal Article

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

Thompson, Vivian P,

Holman, Rury R,

Ramachandran, Ambady,

Maggioni, Aldo P,

Chan, Juliana C,

Poulter, Neil,

Hernandez, Adrian F,

Öhman, Peter,

Mentz, Robert J,

Gustavson, Stephanie M,

Iqbal, Nayyar,

Lokhnygina, Yuliya,

Buse, John B,

Marso, Steven P,

Bethel, M. Angelyn,

Pagidipati, Neha J,

Zinman, Bernard,

Choi, Jasmine

2017

Overview

This trial, which compared once-weekly exenatide plus usual care with usual care alone in patients with type 2 diabetes with or without previous cardiovascular disease, showed no significant between-group difference in the rates of major adverse cardiovascular events.

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Publisher

Massachusetts Medical Society

Subject

Aged

/ Amylin

/ Antidiabetics

/ Cardiovascular disease

/ Cardiovascular Diseases - complications

/ Cardiovascular Diseases - epidemiology

/ Cardiovascular Diseases - mortality