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The Role of Unsaturated Fatty Acid-Rich Dairy Products in Adipocyte Metabolism
by
Silva, Sara
, Machado, Manuela
, Costa, Eduardo M.
, Gomes, Ana Maria
, Pintado, Manuela
in
3T3-L1 Cells
/ Adipocyte metabolism
/ Adipocytes
/ Adipocytes - drug effects
/ Adipocytes - metabolism
/ Amino acids
/ Animals
/ Body fat
/ Caco-2 Cells
/ Chronic illnesses
/ Cytokines - metabolism
/ Dairy industry
/ Dairy products
/ Dairy Products - analysis
/ Energy
/ Fatty acid permeability
/ Fatty acids
/ Fatty Acids, Unsaturated - metabolism
/ Functional food
/ HT29 Cells
/ Humans
/ Inflammation
/ Inflammatory cytokines
/ Insulin resistance
/ Leptin
/ Lipid Metabolism - drug effects
/ Lipolysis - drug effects
/ Metabolism
/ Mice
/ Obesity
/ Permeability
/ Physiological aspects
/ Polyunsaturated fatty acids
/ Saturated fatty acids
/ Type 2 diabetes
/ Unsaturated fatty acids
/ Weight control
/ Yogurt
/ Yogurt - analysis
2024
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The Role of Unsaturated Fatty Acid-Rich Dairy Products in Adipocyte Metabolism
by
Silva, Sara
, Machado, Manuela
, Costa, Eduardo M.
, Gomes, Ana Maria
, Pintado, Manuela
in
3T3-L1 Cells
/ Adipocyte metabolism
/ Adipocytes
/ Adipocytes - drug effects
/ Adipocytes - metabolism
/ Amino acids
/ Animals
/ Body fat
/ Caco-2 Cells
/ Chronic illnesses
/ Cytokines - metabolism
/ Dairy industry
/ Dairy products
/ Dairy Products - analysis
/ Energy
/ Fatty acid permeability
/ Fatty acids
/ Fatty Acids, Unsaturated - metabolism
/ Functional food
/ HT29 Cells
/ Humans
/ Inflammation
/ Inflammatory cytokines
/ Insulin resistance
/ Leptin
/ Lipid Metabolism - drug effects
/ Lipolysis - drug effects
/ Metabolism
/ Mice
/ Obesity
/ Permeability
/ Physiological aspects
/ Polyunsaturated fatty acids
/ Saturated fatty acids
/ Type 2 diabetes
/ Unsaturated fatty acids
/ Weight control
/ Yogurt
/ Yogurt - analysis
2024
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Do you wish to request the book?
The Role of Unsaturated Fatty Acid-Rich Dairy Products in Adipocyte Metabolism
by
Silva, Sara
, Machado, Manuela
, Costa, Eduardo M.
, Gomes, Ana Maria
, Pintado, Manuela
in
3T3-L1 Cells
/ Adipocyte metabolism
/ Adipocytes
/ Adipocytes - drug effects
/ Adipocytes - metabolism
/ Amino acids
/ Animals
/ Body fat
/ Caco-2 Cells
/ Chronic illnesses
/ Cytokines - metabolism
/ Dairy industry
/ Dairy products
/ Dairy Products - analysis
/ Energy
/ Fatty acid permeability
/ Fatty acids
/ Fatty Acids, Unsaturated - metabolism
/ Functional food
/ HT29 Cells
/ Humans
/ Inflammation
/ Inflammatory cytokines
/ Insulin resistance
/ Leptin
/ Lipid Metabolism - drug effects
/ Lipolysis - drug effects
/ Metabolism
/ Mice
/ Obesity
/ Permeability
/ Physiological aspects
/ Polyunsaturated fatty acids
/ Saturated fatty acids
/ Type 2 diabetes
/ Unsaturated fatty acids
/ Weight control
/ Yogurt
/ Yogurt - analysis
2024
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The Role of Unsaturated Fatty Acid-Rich Dairy Products in Adipocyte Metabolism
Journal Article
The Role of Unsaturated Fatty Acid-Rich Dairy Products in Adipocyte Metabolism
2024
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Overview
This study investigated the fatty acid profile, permeability, and metabolic effects of a functional yogurt enriched with pomegranate oil, focusing on its impact on lipid metabolism and inflammatory responses. The yogurt’s fatty acid composition was primarily composed of long-chain polyunsaturated fatty acids (54.37%), followed by saturated (29.34%) and monounsaturated fatty acids (16.36%). During in vitro digestion, a shift in fatty acid profile was observed, with a decrease in polyunsaturated and saturated fatty acids and a slight increase in monounsaturated fatty acids due to hydrolysis. This study further analyzed fatty acid permeability across Caco-2/HT29-MTX monolayers and 3T3-L1 cell uptake, revealing higher permeability for saturated fatty acids than unsaturated ones. In 3T3-L1 cells, permeated fatty acids induced higher lipolysis and increased adiponectin secretion without affecting leptin levels. Cytokine analysis indicated a decrease in pro-inflammatory markers, such as MCP-1, and a significant increase in anti-inflammatory cytokines like IL-10, suggesting potential benefits in reducing obesity-related inflammation. These results underscore the role of functional yogurts enriched with polyunsaturated fatty acids as promising agents for modulating lipid metabolism and inflammatory responses.
Publisher
MDPI AG,MDPI
Subject
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