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Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa
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Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa
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Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa
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Journal Article
Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa
2017
Overview
In this paper, we discuss the potential value of combination therapy with three currently approved drugs (ivermectin, DEC, and albendazole, or IDA) for advancing LF and onchocerciasis elimination programs in Africa. Because Mansonella streptocerca has a limited geographical distribution, usually produces low Mf densities, and is highly susceptible to both DEC and ivermectin, IDA is likely to be safe for use in persons with that infection.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Albendazole - administration & dosage
/ Albendazole - therapeutic use
/ Analysis
/ Anthelmintics - administration & dosage
/ Anthelmintics - therapeutic use
/ Complications and side effects
/ Diethylcarbamazine - administration & dosage
/ Diethylcarbamazine - therapeutic use
/ Elephantiasis, Filarial - drug therapy
/ Elephantiasis, Filarial - epidemiology
/ Elephantiasis, Filarial - prevention & control
/ Humans
/ Ivermectin - administration & dosage
/ Ivermectin - therapeutic use
/ Medicine
/ Medicine and Health Sciences
/ Onchocerciasis - drug therapy
/ Onchocerciasis - epidemiology
/ Onchocerciasis - prevention & control
/ Research and Analysis Methods
/ Studies
