Journal Article

Validation of the Cardiac Arrest Survival Postresuscitation In-hospital (CASPRI) score in an East Asian population

Tsai, Min-Shan, Chang, Wei-Tien, Chen, Wen-Jone, Yu, Ping-Hsun, Wu, Yen-Wen, Huang, Chien-Hua, Wang, Chih-Hung

2018

Overview

The Cardiac Arrest Survival Postresuscitation In-hospital (CASPRI) score is a useful tool for predicting neurological outcome following in-hospital cardiac arrest (IHCA), and was derived from a cohort selected from the Get With The Guidelines-Resuscitation registry between 2000 and 2009 in the United States. In an East Asian population, we aimed to identify the factors associated with outcomes of resuscitated IHCA patients and assess the validity of the CASPRI score. A retrospective study was conducted in a single centre in Taiwan. Patients with IHCA between 2006 and 2014 were screened. Among the 796 included patients, 94 (11.8%) patients achieved neurologically intact survival. Multivariable logistic regression analyses identified factors significantly associated with neurological outcome. Six of these factors were also components of the CASPRI score, including duration of resuscitation, neurological status before IHCA, malignant disease, initial arrest rhythms, renal insufficiency and age. In univariate logistic regression analysis, the CASPRI score was significantly associated with neurological outcome (odds ratio [OR]: 0.83, 95% confidence interval [CI]: 0.80-0.87); the area under the receiver operating characteristics curve was 0.79 (95% CI: 0.74-0.84). In this retrospective study conducted in a single centre at Taiwan, we identified the common prognosticators of IHCA shared by both East Asian and Western societies. As a composite prognosticator, CASPRI score predicts outcomes with excellent accuracy among successfully resuscitated IHCA patients in an East Asian population. This tool allows accurate IHCA prognostication in an East Asian population.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Aged / Cardiac arrest / Cardiology / Cardiopulmonary Resuscitation / Care and treatment / Confidence intervals / Councils / CPR / Decision Making / Emergency medical care / Far East - epidemiology / Female / Health aspects / Heart / Heart Arrest - physiopathology / Heart Arrest - therapy / Hospitals / Humans / Intensive care / Internal medicine / Logistic Models / Male / Medicine and Health Sciences / Middle Aged / Mortality / Multivariate Analysis / Nuclear medicine / Palliative care / Patient outcomes / Patients / People and Places / Physical Sciences / Population / Prognosis / Regression analysis / Renal insufficiency / Research and Analysis Methods / Resuscitation / Retrospective Studies / Risk factors / Sepsis / Statistical analysis / Survival / Survival Analysis / Taiwan - epidemiology / Time Factors / Treatment Outcome