Asset Details
Do you wish to reserve the book?
New Strains of Bacteria and Exacerbations of Chronic Obstructive Pulmonary Disease
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
New Strains of Bacteria and Exacerbations of Chronic Obstructive Pulmonary Disease
Do you wish to request the book?
New Strains of Bacteria and Exacerbations of Chronic Obstructive Pulmonary Disease
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
New Strains of Bacteria and Exacerbations of Chronic Obstructive Pulmonary Disease
2002
Overview
This prospective study examined the changes in bacterial isolates from sputum samples obtained monthly from 81 outpatients with chronic obstructive pulmonary disease. There were 374 acute exacerbations of lung disease, which were significantly associated with the acquisition of a new strain of
Haemophilus influenzae, Moraxella catarrhalis,
or
Streptococcus pneumoniae
(relative risk for any new strain, 2.15). An exacerbation was diagnosed at 33 percent of the clinic visits that coincided with the appearance of a new bacterial strain in the sputum.
This prospective study shows a relation between clinical deterioration and the presence of a new bacterial strain.
Morbidity and mortality among patients with chronic obstructive pulmonary disease are related in large part to acute exacerbations, which occur one to three times per year.
1
–
6
Our understanding of the cause and pathogenesis of these exacerbations is incomplete, and the role of bacterial pathogens is controversial.
7
–
10
In studies performed decades ago, investigators followed patients with chronic obstructive pulmonary disease longitudinally, with periodic collection of sputum samples for culture, to determine whether there was an association between the isolation of bacterial pathogens in sputum and the occurrence of exacerbations.
5
,
6
,
11
In these studies, the rate of isolation of . . .
Publisher
Massachusetts Medical Society
Subject
/ Bacteria - isolation & purification
/ Biological and medical sciences
/ Chronic obstructive pulmonary disease
/ Chronic obstructive pulmonary disease, asthma
/ Female
/ Haemophilus influenzae - classification
/ Haemophilus influenzae - isolation & purification
/ Humans
/ Male
/ Moraxella (Branhamella) catarrhalis - classification
/ Moraxella (Branhamella) catarrhalis - isolation & purification
/ Pulmonary Disease, Chronic Obstructive - complications
/ Pulmonary Disease, Chronic Obstructive - microbiology
/ Staphylococcus aureus - classification
/ Staphylococcus aureus - isolation & purification
/ Streptococcus pneumoniae - classification
/ Streptococcus pneumoniae - isolation & purification
/ Studies
