Journal Article

Combining OSTA and BMR to predict osteoporosis in Chinese population

Wang, Shuo, Wang, Yulin, Guo, Qin, Wang, Wei, Song, Jidong, Zhao, Jiaxin

2024

Overview

Introduction Osteoporosis is a debilitating bone disease that significantly contributes to disability and a loss of autonomy among older adults. This study aimed to characterize osteoporosis and explore the feasibility of combining OSTA and BMR for osteoporosis prediction. Methods A cross-sectional study involving 1435 participants (1300 women and 135 men) was conducted. Spearman’s correlation, simple linear regression analyses, and multiple linear regression models were utilized to investigate the association between OSTA, BMR, and bone mineral density (BMD). Furthermore, the efficacy of integrating OSTA with BMR for osteoporosis screening and prediction was assessed through receiver operating characteristic (ROC) curves. Results In the total population, the sensitivity of combination variable W was 58.63%, and the specificity was 70.90%. When OSTA and BMR were employed separately to diagnose osteoporosis, the sensitivity was 47.70% and 55.34%, respectively, while the specificity was 63.80% and 69.80%, respectively. Conclusions The combined utilization of OSTA and BMR formula represents an effective screening method for osteoporosis.

• Publisher: BioMed Central,BioMed Central Ltd,BMC
• Subject: Aged / Aged, 80 and over / Analysis / BMR / Bone Density / China / China - epidemiology / Cross-Sectional Studies / East Asian People / Female / Humans / Male / Mass Screening - methods / Medicine / Medicine & Public Health / Middle Aged / New Horizons in Smart Orthopaedic Implants: Advances and Applications / Orthopedics / OSTA / Osteoporosis / Osteoporosis - diagnosis / Predictive Value of Tests / Research Article / Sensitivity and Specificity / Surgical Orthopedics