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Cross-Protective Capacity of Japanese Encephalitis (JE) Vaccines Against Circulating Heterologous JE Virus Genotypes

by Erra, Elina O. , Riutta, Jukka , Kantele, Anu , Askling, Helena Hervius , Rombo, Lars , Vapalahti, Olli , Lindquist, Lars , Yoksan, Sutee , Vene, Sirkka

in Adolescent / Adult / Antibodies, Neutralizing - immunology / Antibodies, Viral - immunology / Arboviral encephalitis / Arboviroses / Biological and medical sciences / BRIEF REPORT / Cross Reactions - immunology / Encephalitis / Encephalitis Virus, Japanese - genetics / Encephalitis Virus, Japanese - immunology / Encephalitis, Japanese - immunology / Encephalitis, Japanese - prevention & control / Female / Genotype / Genotype & phenotype / Genotypes / Human viral diseases / Humans / Immune response / Infectious diseases / Japanese encephalitis / Japanese encephalitis vaccines / Japanese Encephalitis Vaccines - immunology / Japanese encephalitis viruses / Male / Medical sciences / Middle Aged / Miscellaneous / Neutralizing antibodies / Polyclonal antibodies / Travelers / Tropical viral diseases / Vaccination / Vaccines / Vaccines, Inactivated - immunology / Vector-borne diseases / Viral diseases / Viruses / Young Adult

2013

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Cross-Protective Capacity of Japanese Encephalitis (JE) Vaccines Against Circulating Heterologous JE Virus Genotypes

by Erra, Elina O. , Riutta, Jukka , Kantele, Anu , Askling, Helena Hervius , Rombo, Lars , Vapalahti, Olli , Lindquist, Lars , Yoksan, Sutee , Vene, Sirkka

2013

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Cross-Protective Capacity of Japanese Encephalitis (JE) Vaccines Against Circulating Heterologous JE Virus Genotypes

by Erra, Elina O. , Riutta, Jukka , Kantele, Anu , Askling, Helena Hervius , Rombo, Lars , Vapalahti, Olli , Lindquist, Lars , Yoksan, Sutee , Vene, Sirkka

2013

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Journal Article

Cross-Protective Capacity of Japanese Encephalitis (JE) Vaccines Against Circulating Heterologous JE Virus Genotypes

Erra, Elina O.,

Riutta, Jukka,

Kantele, Anu,

Askling, Helena Hervius,

Rombo, Lars,

Vapalahti, Olli,

Lindquist, Lars,

Yoksan, Sutee,

Vene, Sirkka

2013

Overview

Current Japanese encephalitis vaccines are derived from strains of genotype III, yet heterologous genotypes are emerging in endemic areas. Inactivated vaccines given to European travelers were found to elicit protective levels of neutralizing anti-bodies against heterologous strains of genotypes I–IV.

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Publisher

Oxford University Press

Subject

Adolescent

/ Adult

/ Antibodies, Neutralizing - immunology

/ Antibodies, Viral - immunology

/ Arboviral encephalitis

/ Arboviroses

/ Biological and medical sciences