Journal Article

Exploring Risk Factors Associated With Early Mother's Own Milk Feeding Cessation in Very Low Birth Weight Infants

Rüffer, Jens Ulrich, Rupprecht, Christoph, Matthias, Katja, Horenkamp‐Sonntag, Dirk, Klein, Melanie, Wiesen, Daniel, Hammer, Antje, Mildenberger, Eva, Eyssel, Friederike, Lugani, Katharina, Kribs, Angela, Hellmich, Martin, Kurz, Anke, Müller, Andreas, Klein, Iris, Ohnhäuser, Tim, Karacan, Kaan, Schleich, Laura, Dresbach, Till, Scholten, Nadine, Schwab, Isabella, Köberlein‐Neu, Juliane, Ernstmann, Nicole, Beckmann, Olaf, Sunder‐Plaßmann, Anne

2025

Overview

Infants born with a very low birth weight (VLBW, < = 1.500 g) have an increased risk for medical complications and long‐term impairments. Feeding these infants with their mother's own milk (MOM) reduces the risk for adverse outcomes, but many VLBW infants are not fed with MOM for the recommended duration of at least 6 months postpartum. This study examines factors associated with early cessation during the VLBW infants' neonatal intensive care unit (NICU) stay and after discharge. Data were collected from an anonymous, nationwide survey as part of the Neo‐MILK study. Logistic regressions and Cox proportional hazard models were used to identify factors associated with early cessation of MOM feeding. Among the 304 mothers analysed, 19.4% of all mothers ceased MOM feeding during the infants' NICU stay. The total cessation rate before 6 months was 53.9%. An early milk volume of over 500 mL/day compared to less or equal to 500 mL/day was negatively associated with MOM feeding cessation during the infants' NICU stay (Adjusted OR: 0.14). Exclusive pumping was associated with a higher cessation rate after discharge (Adjusted HR: 2.01). Early sufficient milk volume and mixed feeding (pumping and breastfeeding) inform longer MOM feeding duration. Interventions targeting early lactation practices and promoting direct breastfeeding while helping with the transition from pumping to breastfeeding are essential for improving MOM feeding outcomes in VLBW infants. Trial Registration: German Register of Clinical Trials, ID: DRKS00024799, https://drks.de/search/en/trial/DRKS00024799. Early cessation of mother's own milk (MOM) feeding in very low birth weight infants is strongly linked to low milk volume by Day 14 postpartum and exclusive pumping after discharge. Promoting early lactation support and mixed feeding (pumping and breastfeeding) strategies may help extend MOM feeding duration. Summary Professional lactation support is vital during the NICU stay, especially for mothers of VLBW infants who struggle to reach a milk volume of 500 mL/day by Day 14 postpartum. Exclusive pumping is associated with a higher risk of early cessation, highlighting the need to promote a combination of pumping and breastfeeding while supporting the mothers during the transition to direct breastfeeding. Given the unique challenges faced by mothers of VLBW infants, focused interventions are essential to extend MOM feeding durations and thus improve health outcomes for both mother and infant.

• Publisher: John Wiley & Sons, Inc,Wiley
• Subject: Adult / Birth weight / Breast feeding / Breast Feeding - statistics & numerical data / Breast Milk Expression / breastfeeding / Breastfeeding & lactation / Clinical outcomes / Clinical research / Clinical trials / Discharge / Early intervention / Female / human milk / Humans / infant / Infant Nutritional Physiological Phenomena / Infant, Newborn / Infant, Very Low Birth Weight - growth & development / Infants / Intensive care / Intensive Care Units, Neonatal / lactation / Low birth weight / Male / Milk / Milk, Human / Mothers / Neonatal units / Original / Postpartum period / Registration / Risk / Risk Factors / Risk reduction / survival analysis / very low birth weight / Young Adult