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The Role of the Plasma from Platelet Concentrates in Transfusion Reactions
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The Role of the Plasma from Platelet Concentrates in Transfusion Reactions
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Journal Article
The Role of the Plasma from Platelet Concentrates in Transfusion Reactions
1994
Overview
Febrile, nonhemolytic transfusion reactions are the most frequent adverse reactions to blood products. The risk of these reactions is highest with platelets; they occur in 5 to 30 percent of platelet transfusions, depending on the type of product
1
–
3
. Most of the reactions are mild, but some are life-threatening. The widespread practice of premedication with antipyretic agents often prevents fever, but not the other unpleasant side effects of the reactions
2
.
The mechanism of reactions to transfused platelets is not well understood. It is generally assumed that they are caused by the interaction of antileukocyte alloantibodies in the recipient's . . .
Publisher
Massachusetts Medical Society
Subject
/ Age
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Biological and medical sciences
/ Humans
/ Interleukin-1 - adverse effects
/ Interleukin-6 - adverse effects
/ Leukemia, Myeloid, Acute - therapy
/ Patients
/ Plasma
/ Platelet Transfusion - adverse effects
/ Thrombocytopenia - immunology
/ Transfusions. Complications. Transfusion reactions. Cell and gene therapy
