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Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study

by Sin, Yoong Kong , Tan, Teing Ee , Loh, Yee Jim , Pang, Philip Y.K. , Kerk, Ka Lee , Wee, Gillian H.L. , Lim, See Lim , Lim, Chong Hee , Hoo, Anne E.E. , Tahir Sheriff, Ismail Mohamed

in Adult / Adults / Cardiac arrest / Cardiac Surgery / Cardiopulmonary Resuscitation / Care and treatment / Central Nervous System Diseases - etiology / Complications and side effects / Extracorporeal Membrane Oxygenation / Female / Health aspects / Heart Arrest - complications / Heart Arrest - therapy / Humans / Hypothermia / Hypothermia, Induced - adverse effects / Letter to the Editor / Male / Medicine / Medicine & Public Health / Middle Aged / Risk factors / Thoracic Surgery

2016

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Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study

by Sin, Yoong Kong , Tan, Teing Ee , Loh, Yee Jim , Pang, Philip Y.K. , Kerk, Ka Lee , Wee, Gillian H.L. , Lim, See Lim , Lim, Chong Hee , Hoo, Anne E.E. , Tahir Sheriff, Ismail Mohamed

2016

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Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study

by Sin, Yoong Kong , Tan, Teing Ee , Loh, Yee Jim , Pang, Philip Y.K. , Kerk, Ka Lee , Wee, Gillian H.L. , Lim, See Lim , Lim, Chong Hee , Hoo, Anne E.E. , Tahir Sheriff, Ismail Mohamed

2016

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Journal Article

Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study

Sin, Yoong Kong,

Tan, Teing Ee,

Loh, Yee Jim,

Pang, Philip Y.K.,

Kerk, Ka Lee,

Wee, Gillian H.L.,

Lim, See Lim,

Lim, Chong Hee,

Hoo, Anne E.E.,

Tahir Sheriff, Ismail Mohamed

2016

Overview

Cardiac arrest with cerebral ischaemia frequently leads to severe neurological impairment. Extracorporeal life support (ECLS) has emerged as a valuable adjunct in resuscitation of cardiac arrest. Despite ECLS, the incidence of permanent neurological injury remains high. We hypothesize that patients receiving ECLS for cardiac arrest treated with therapeutic hypothermia at 34 °C have lower neurological complication rates compared to standard ECLS therapy at normothermia. Early results of this randomized study suggest that therapeutic hypothermia is safe in adult patients receiving ECLS, with similar complication rates as ECLS without hypothermia. Further studies are warranted to measure the efficacy of this therapy.

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Publisher

BioMed Central,BioMed Central Ltd,Springer Nature B.V

Subject

Adult

/ Adults

/ Cardiac arrest

/ Cardiac Surgery

/ Cardiopulmonary Resuscitation

/ Care and treatment

/ Central Nervous System Diseases - etiology