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Protein interaction data curation: the International Molecular Exchange (IMEx) consortium

by Bhate, Jignesh , Lynn, David J , Mahadevan, Usha , Roechert, Bernd , Cesareni, Gianni , Chen, Carol , Goll, Johannes , Briganti, Leonardo , Kerrien, Samuel , Tyers, Mike , Aranda, Bruno , Chatr-aryamontri, Andrew , Hancock, Robert E W , Dumousseau, Marine , Hannick, Linda I , Jurisica, Igor , Perfetto, Livia , Abbani, Sara , Chautard, Emilie , Salwinski, Lukasz , Bridge, Alan , Khadake, Jyoti , Hermjakob, Henning , Bidwell, Shelby , Xenarios, Ioannis , Raghunath, Arathi , Brinkman, Fiona S L , Ricard-Blum, Sylvie , Uetz, Peter , Orchard, Sandra , Stümpflen, Volker

in 631/1647/48 / 631/45/475 / Alliances and partnerships / Bioinformatics / Biological Microscopy / Biological Techniques / Biomedical and Life Sciences / Biomedical Engineering/Biotechnology / Consortia / Databases, Protein / International cooperation / Life Sciences / Molecular biology / Periodicals as Topic / perspective / Protein Binding / Protein Interaction Mapping / Proteins / Proteins - chemistry / Proteins - metabolism / Proteomics / Quality Control

2012

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2012

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2012

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Journal Article

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium

Bhate, Jignesh,

Lynn, David J,

Mahadevan, Usha,

Roechert, Bernd,

Cesareni, Gianni,

Chen, Carol,

Goll, Johannes,

Briganti, Leonardo,

Kerrien, Samuel,

Tyers, Mike,

Aranda, Bruno,

Chatr-aryamontri, Andrew,

Hancock, Robert E W,

Dumousseau, Marine,

Hannick, Linda I,

Jurisica, Igor,

Perfetto, Livia,

Abbani, Sara,

Chautard, Emilie,

Salwinski, Lukasz,

Bridge, Alan,

Khadake, Jyoti,

Hermjakob, Henning,

Bidwell, Shelby,

Xenarios, Ioannis,

Raghunath, Arathi,

Brinkman, Fiona S L,

Ricard-Blum, Sylvie,

Uetz, Peter,

Orchard, Sandra,

Stümpflen, Volker

2012

Overview

Presented is an update on the status and current practices of the International Molecular Exchange (IMEx) consortium and on its efforts to create a single nonredundant set of protein interactions curated from the scientific literature. The International Molecular Exchange (IMEx) consortium is an international collaboration between major public interaction data providers to share literature-curation efforts and make a nonredundant set of protein interactions available in a single search interface on a common website ( http://www.imexconsortium.org/ ). Common curation rules have been developed, and a central registry is used to manage the selection of articles to enter into the dataset. We discuss the advantages of such a service to the user, our quality-control measures and our data-distribution practices.

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Publisher

Nature Publishing Group US,Nature Publishing Group

Subject

631/1647/48

/ 631/45/475

/ Alliances and partnerships

/ Bioinformatics

/ Biological Microscopy

/ Biological Techniques

/ Biomedical and Life Sciences