Journal Article

Ganoderma spore powder contains little triterpenoids

Liu, Mei-Ting, Li, Shao-Ping, Chen, Ling-Xiao, Zhao, Jing

2020

Overview

Background Ganoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period, it has been considered with high exploitable potential in health-care products manufacture. Methods After testing sporoderm-broken rate, the triterpenoids in 12 batches of broken and unbroken Ganoderma spore powder (GSP) samples were compared with Ganoderma lucidum fruiting body (GL) by high performance thin-layer chromatography (HPTLC) and further verified by liquid chromatography coupled with electrospray ionization quadrupole-time-of-flight mass spectrometry (LC–QTOF–MS); meanwhile, the dissolution of triterpenoids after bionic extraction was also investigated by HPTLC. Results The sporoderm-broken rate of all the broken GSP samples was over 85%. The relative peak area of triterpenoids in GSP samples were lower than 50% of that in fruiting body, and the dissolution of triterpenoids in artificial gastrointestinal fluid was lower than in methanol. Conclusions This study demonstrated that there were little triterpenoids in GSP. Triterpenoids in GSP also seldom be dissolved in artificial gastrointestinal fluid.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Acupuncture / Antifungal agents / Artificial gastroenteric fluid / Bionic extraction / Complementary & Alternative Medicine / Dissolution / Fruit bodies / Ganoderma / Ganoderma spore powder / Gills / HPTLC / Ionization / LC–QTOF–MS / Liquid chromatography / Mass spectrometry / Mass spectroscopy / Medicine / Medicine & Public Health / Membrane filters / Powders (Particulate matter) / Thin-layer chromatography / Traditional Chinese Medicine / Triterpenoids