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Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

by Abad, M , Gill, D , Chondronasiou, D , Fernández Fraga, Mario , Serrano, M , Kroemer, G , Berenguer Llergo, A , Martin Herranz, D. E , González Urdinguio, Rocío , Durand, S , Mosteiro, L , Aprahamian, F , Aguilera, M , Nirmalathasan, N , Prats, N , Reik, W , Stephan Otto Attolini, C

in Age / Aging / Animals / Cell Differentiation / Cellular Reprogramming - genetics / DNA damage / DNA methylation / DNA Methylation - genetics / epigenetic clocks / Epigenetics / Epigenome / Induced Pluripotent Stem Cells - metabolism / KLF4 protein / Metabolomics / Mice / Myc protein / Oct-4 protein / OSKM / Pancreas / Pluripotency / Rejuvenation / reprogramming / Spleen / Stem cell transplantation / Stem cells / Transcription / Transcription factors / Transcriptomes / transcriptomic clocks / Transcriptomics / Yamanaka

2022

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Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

2022

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Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

2022

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Journal Article

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Abad, M,

Gill, D,

Chondronasiou, D,

Fernández Fraga, Mario,

Serrano, M,

Kroemer, G,

Berenguer Llergo, A,

Martin Herranz, D. E,

González Urdinguio, Rocío,

Durand, S,

Mosteiro, L,

Aprahamian, F,

Aguilera, M,

Nirmalathasan, N,

Prats, N,

Reik, W,

Stephan Otto Attolini, C

2022

Overview

H2020 European Research Council, Grant/Award Number: ERC-2014-AdG/669622; Fundación Científica Asociación Española Contra el Cáncer, Grant/Award Number: PROYE18061FERN; Ministerio de Ciencia e Innovación, Grant/Award Number: SAF2013-48256-R; the Asturias Regionla Government (PCTI) co-funding 2018- 2022/FEDER (IDI/2018/146), the Health Institute Carlos III (Plan Nacional de I+D+I) co-funding FEDER (PI18/01527)...

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Publisher

John Wiley & Sons, Inc,John Wiley and Sons Inc

Subject

Age

/ Aging

/ Animals

/ Cell Differentiation

/ Cellular Reprogramming - genetics

/ DNA damage

/ DNA methylation