Asset Details
Do you wish to reserve the book?
Stress injuries and autophagy in mouse hippocampus after chronic cold exposure
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Stress injuries and autophagy in mouse hippocampus after chronic cold exposure
Do you wish to request the book?
Stress injuries and autophagy in mouse hippocampus after chronic cold exposure
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Stress injuries and autophagy in mouse hippocampus after chronic cold exposure
2017
Overview
Cold exposure is an external stress factor that causes skin frostbite as well as a variety of diseases.Estrogen might participate in neuroprotection after cold exposure,but its precise mechanism remains unclear.In this study,mice were exposed to 10°C for 7 days and 0–4°C for 30 days to induce a model of chronic cold exposure.Results showed that oxidative stress-related c-fos and cyclooxygenase 2 expressions,MAP1LC3-labeled autophagic cells,Iba1-labeled activated microglia,and interleukin-1β-positive pyramidal cells were increased in the hippocampal CA1 area.Chronic cold exposure markedly elevated the levels of estrogen in the blood and the estrogen receptor,G protein-coupled receptor 30.These results indicate that neuroimmunoreactivity is involved in chronic cold exposure-induced pathological alterations,including oxidative stress,neuronal autophagy,and neuroimmunoreactivity.Moreover,estrogen exerts a neuroprotective effect on cold exposure.
Publisher
Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Institute of Neurobiology,College of Life Science,Henan University,Kaifeng,Henan Province,China,Nursing College,Henan Vocational College of Applied Technology,Zhengzhou,Henan Province,China%Institute of Neurobiology,College of Life Science,Henan University,Kaifeng,Henan Province,China,Medknow Publications & Media Pvt Ltd,Wolters Kluwer Medknow Publications
