Asset Details
Do you wish to reserve the book?
Viral Glycosphingolipids Induce Lytic Infection and Cell Death in Marine Phytoplankton
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Viral Glycosphingolipids Induce Lytic Infection and Cell Death in Marine Phytoplankton
Do you wish to request the book?
Viral Glycosphingolipids Induce Lytic Infection and Cell Death in Marine Phytoplankton
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Viral Glycosphingolipids Induce Lytic Infection and Cell Death in Marine Phytoplankton
2009
Overview
Marine viruses that infect phytoplankton are recognized as a major ecological and evolutionary driving force, shaping community structure and nutrient cycling in the marine environment. Little is known about the signal transduction pathways mediating viral infection. We show that viral glycosphingolipids regulate infection of Emiliania huxleyi, a cosmopolitan coccolithophore that plays a major role in the global carbon cycle. These sphingolipids derive from an unprecedented cluster of biosynthetic genes in Coccolithovirus genomes, are synthesized de novo during lytic infection, and are enriched in virion membranes. Purified glycosphingolipids induced biochemical hallmarks of programmed cell death in an uninfected host. These lipids were detected in coccolithophore populations in the North Atlantic, which highlights their potential as biomarkers for viral infection in the oceans.
Publisher
American Association for the Advancement of Science,The American Association for the Advancement of Science
Subject
/ Animal, plant and microbial ecology
/ Biological and medical sciences
/ Fundamental and applied biological sciences. Psychology
/ genes
/ Glycosphingolipids - analysis
/ Glycosphingolipids - biosynthesis
/ Glycosphingolipids - physiology
/ Lipids
/ Marine
/ Oceans
/ Phycodnaviridae - isolation & purification
/ Phycodnaviridae - physiology
/ Plankton
/ virion
/ Virions
/ Viruses
