Journal Article

Botrytis cinerea virulence factors:new insights into a necrotrophic and polyphageous pathogen

Pradier, Jean-Marc, Choquer, Mathias, Kunz, Caroline, Levis, Caroline, Simon, Adeline, Fournier, Elisabeth, Viaud, Muriel

2007

Overview

Botrytis cinerea is responsible for the gray mold disease on more than 200 host plants. This necrotrophic ascomycete displays the capacity to kill host cells through the production of toxins, reactive oxygen species and the induction of a plant-produced oxidative burst. Thanks to an arsenal of degrading enzymes, B. cinerea is then able to feed on different plant tissues. Recent molecular approaches, for example on characterizing components of signal transduction pathways, show that this fungus shares conserved virulence factors with other phytopathogens, but also highlight some Botrytis-specific features. The discovery of some first strain-specific virulence factors, together with population data, even suggests a possible host adaptation of the strains. The availability of the genome sequence now stimulates the development of high-throughput functional analysis to decipher the mechanisms involved in the large host range of this species.

• Publisher: Wiley-Blackwell,HAL CCSD,Oxford, UK : Blackwell Publishing Ltd,Blackwell Publishing Ltd,Blackwell,Oxford University Press
• Subject: Ascomycetes / Bacteriology / Biological and medical sciences / Botrytis / Botrytis - classification / Botrytis - genetics / Botrytis - pathogenicity / Botrytis - physiology / Botrytis cinerea / classification / enzymes / Fabaceae / Fabaceae - microbiology / Functional analysis / Fundamental and applied biological sciences. Psychology / Fungal Proteins / Fungal Proteins - genetics / Fungal Proteins - metabolism / Fungi / genetics / Genomes / gray mold / Grey mold / host adaptation / Host plants / Host range / Life Sciences / metabolism / Microbiology / Microbiology and Parasitology / Mycotoxins / Mycotoxins - metabolism / Nucleotide sequence / nucleotide sequences / pathogenicity / Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains / physiology / Plant Diseases / Plant Diseases - microbiology / Plant Leaves / Plant Leaves - microbiology / plant pathogens / Plant tissues / Reactive oxygen species / Respiratory Burst / Signal Transduction / Toxins / Virulence / Virulence Factors / Virulence Factors - genetics / Virulence Factors - metabolism