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20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

by Dowsett, Mitch , Hayes, Daniel F , Braybrooke, Jeremy , Pritchard, Kathleen I , Bergh, Jonas , Davies, Christina , Gray, Richard , Peto, Richard , McGale, Paul , Pan, Hongchao , Taylor, Carolyn

in Adult / Age / Aged / Breast cancer / Breast Neoplasms - drug therapy / Breast Neoplasms - mortality / Breast Neoplasms - pathology / Cancer and Oncology / Cancer och onkologi / Chemotherapy, Adjuvant / Clinical Medicine / Clinical outcomes / Clinical trials / Drug Administration Schedule / Endocrine therapy / Epidermal growth factor / ErbB-2 protein / Estrogen Antagonists - therapeutic use / Estrogen receptors / Female / Humans / Kaplan-Meier Estimate / Klinisk medicin / Lymphatic Metastasis / Lymphatic system / Medical and Health Sciences / Medical research / Medicin och hälsovetenskap / Middle Aged / Monoclonal antibodies / Neoplasm Grading / Neoplasm Metastasis / Neoplasm Recurrence, Local / Patients / Progesterone / Prognosis / Proportional Hazards Models / Receptors, Estrogen / Recurrence / Risk / Systematic review / Targeted cancer therapy / Trastuzumab / Womens health

2017

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20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

by Dowsett, Mitch , Hayes, Daniel F , Braybrooke, Jeremy , Pritchard, Kathleen I , Bergh, Jonas , Davies, Christina , Gray, Richard , Peto, Richard , McGale, Paul , Pan, Hongchao , Taylor, Carolyn

2017

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20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

by Dowsett, Mitch , Hayes, Daniel F , Braybrooke, Jeremy , Pritchard, Kathleen I , Bergh, Jonas , Davies, Christina , Gray, Richard , Peto, Richard , McGale, Paul , Pan, Hongchao , Taylor, Carolyn

2017

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Journal Article

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

Dowsett, Mitch,

Hayes, Daniel F,

Braybrooke, Jeremy,

Pritchard, Kathleen I,

Bergh, Jonas,

Davies, Christina,

Gray, Richard,

Peto, Richard,

McGale, Paul,

Pan, Hongchao,

Taylor, Carolyn

2017

Overview

In a meta-analysis of 88 trials involving nearly 63,000 women with breast cancer who were disease-free after 5 years of endocrine therapy, the risk of recurrence ranged from 10 to 41% between years 5 and 20, depending on nodal status and tumor grade.

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Publisher

Massachusetts Medical Society

Subject

Adult

/ Age

/ Aged

/ Breast cancer

/ Breast Neoplasms - drug therapy

/ Breast Neoplasms - mortality

/ Breast Neoplasms - pathology