Asset Details
Do you wish to reserve the book?
Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison
Do you wish to request the book?
Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison
2021
Overview
Background
Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain.
Methods
In this registry-based study, we assessed 8163 patients who underwent isolated CABG between 2014 and 2016. Propensity score matching (PSM), inverse probability of weighting (IPW) and covariate adjustment were performed to correct for and minimize selection bias.
Results
The overall mean age of the patients was 62 years, and 25.7% were women. Patients who underwent off-pump CABG had shorter length of hospitalization (
p
< 0.001), intubation time (
p
= 0.003) and length of ICU admission (
p
< 0.001). Off-pump CABG was associated with higher risk of 30-days mortality (OR: 1.7; 95% CI 1.09–2.65;
p
= 0.019) in unadjusted analysis. After covariate adjustment and matching (PSM and IPW), this difference was not statistically significant. After an average of 36.1 months follow-up, risk of MACCE and all-cause mortality didn’t have significant differences in both surgical methods by adjusting with IPW (HR: 1.03; 95% CI 0.87–1.24;
p
= 0.714; HR: 0.91; 95% CI 0.73–1.14;
p
= 578, respectively).
Conclusion
Off-pump and on-pump techniques have similar 30-day mortality (adjusted, PSM and IPW). Off-pump surgery is probably more cost-effective in short term; however, mid-term survival and MACCE trends in both surgical methods are comparable.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Cardiopulmonary Bypass - adverse effects
/ Cardiopulmonary Bypass - mortality
/ Cardiopulmonary Bypass - statistics & numerical data
/ Comparative Effectiveness Research
/ Coronary Artery Bypass - adverse effects
/ Coronary Artery Bypass - mortality
/ Coronary Artery Bypass - statistics & numerical data
/ Coronary artery bypass grafting
/ Coronary Artery Bypass, Off-Pump - adverse effects
/ Coronary Artery Bypass, Off-Pump - mortality
/ Coronary Artery Bypass, Off-Pump - statistics & numerical data
/ Coronary Artery Disease - diagnosis
/ Coronary Artery Disease - mortality
/ Coronary Artery Disease - surgery
/ Diabetes
/ Female
/ Heart
/ Humans
/ Male
/ Medicine
/ Methods
/ Off-pump
/ Patients
/ Surgeons
/ Surgery
