Journal Article

Transfemoral transcatheter aortic valve replacement for pure native aortic regurgitation: one-year outcomes of a single-center study

Li, Jun, Yu, San-Jiu, Cheng, Yong-Bo, Cheng, Wei, Lin, De-Qing, He, Ping, Zheng, Hua-Jie, Yan, Chao-Jun

2023

Overview

Background Evidence about safety and efficacy of transcatheter aortic valve replacement (TAVR) with the Venus A-Valve system (Venus Medtech, Hangzhou, China) remains limited for patients with pure native aortic regurgitation (PNAR). Objectives The single-center study sought to report the one-year clinical outcomes of the Venus A-Valve in the treatment of PNAR. Methods This study was a retrospective analysis of prospectively collected data. Data was from all consecutive patients who had PNAR and underwent TAVR with the Venus A-Valve system at our center from July 2020 and June 2021. Procedural and clinical outcomes up to one year were analyzed using Valve Academic Research Consortium-2 criteria. Results A total of 45 consecutive patients with PNAR underwent transfemoral TAVR with the Venus A-Valve system. The Mean age was 73.5 ± 5.5 years and 26.7% were female. All the TAVR procedures were performed via transfemoral access. Implantations were successful in 44 cases (97.8%). Only one patient was converted to surgical aortic valve replacement. No patient died intraoperatively. No second valve was implanted. In-hospital mortality rate was 2.3%. The one-year all-cause mortality rate was 4.7% without cardiovascular related death. No patient had moderate or severe paravalvular leakage during follow-up. At one year, the mean pressure gradient was 8.8 ± 0.9 mmHg, and left ventricular ejection fraction increased to 61.5 ± 3.6%. Conclusions This single-center study demonstrated the safety and efficacy of transfemoral TAVR with the Venus A-Valve in the treatment of patients with PNAR.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Aged / Angiology / Aortic valve / Aortic valve insufficiency / Aortic Valve Insufficiency - diagnostic imaging / Aortic Valve Insufficiency - etiology / Aortic Valve Insufficiency - surgery / Blood Transfusion Medicine / Cardiac Surgery / Cardiology / Care and treatment / Clinical outcomes / Diagnosis / Female / Heart / Heart valve replacement / Humans / Internal Medicine / Male / Medicine / Medicine & Public Health / Mortality / Pacemakers / Patient outcomes / Patients / Prostheses / Pure native aortic regurgitation / Regurgitation / Retrospective Studies / Statistical analysis / Stroke Volume / Tomography / Transcatheter aortic valve replacement / Transcatheter Aortic Valve Replacement - adverse effects / Ventricle / Ventricular Function, Left / Venus A-Valve