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Impact of early surgical complications on kidney transplant outcomes
by
Gupta, Nikita
, Selzner, Markus
, Minkovich, Michelle
, Famure, Olusegun
, Ghanekar, Anand
, Li, Yanhong
, Lee, Jason Y.
, Liu, Michelle
, Kim, S. Joseph
in
Abscesses
/ Adult
/ Aged
/ Analysis
/ Candidates
/ Chronic kidney failure
/ Clinical outcomes
/ Complications and side effects
/ Female
/ Graft Survival
/ Grafting
/ Hematoma
/ Hemoglobin
/ Hospitals
/ Humans
/ Internal Medicine
/ Kidney
/ Kidney Failure, Chronic - surgery
/ Kidney Transplantation
/ Kidney Transplantation - adverse effects
/ Kidney transplants
/ Kidneys
/ Male
/ Medical research
/ Medicine
/ Medicine & Public Health
/ Medicine, Experimental
/ Middle Aged
/ Observational studies
/ Patient outcomes
/ Patient Readmission - statistics & numerical data
/ Patients
/ Postoperative Complications - epidemiology
/ Postoperative Complications - etiology
/ Retrospective Studies
/ Sensitivity analysis
/ Statistical models
/ Surgery
/ Surgical complications
/ Surgical site infections
/ Thrombosis
/ Time Factors
/ Transplantation
/ Treatment Outcome
/ Ultrasonic imaging
/ Variables
/ Veins & arteries
/ Wound dehiscence
2024
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Impact of early surgical complications on kidney transplant outcomes
by
Gupta, Nikita
, Selzner, Markus
, Minkovich, Michelle
, Famure, Olusegun
, Ghanekar, Anand
, Li, Yanhong
, Lee, Jason Y.
, Liu, Michelle
, Kim, S. Joseph
in
Abscesses
/ Adult
/ Aged
/ Analysis
/ Candidates
/ Chronic kidney failure
/ Clinical outcomes
/ Complications and side effects
/ Female
/ Graft Survival
/ Grafting
/ Hematoma
/ Hemoglobin
/ Hospitals
/ Humans
/ Internal Medicine
/ Kidney
/ Kidney Failure, Chronic - surgery
/ Kidney Transplantation
/ Kidney Transplantation - adverse effects
/ Kidney transplants
/ Kidneys
/ Male
/ Medical research
/ Medicine
/ Medicine & Public Health
/ Medicine, Experimental
/ Middle Aged
/ Observational studies
/ Patient outcomes
/ Patient Readmission - statistics & numerical data
/ Patients
/ Postoperative Complications - epidemiology
/ Postoperative Complications - etiology
/ Retrospective Studies
/ Sensitivity analysis
/ Statistical models
/ Surgery
/ Surgical complications
/ Surgical site infections
/ Thrombosis
/ Time Factors
/ Transplantation
/ Treatment Outcome
/ Ultrasonic imaging
/ Variables
/ Veins & arteries
/ Wound dehiscence
2024
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Impact of early surgical complications on kidney transplant outcomes
by
Gupta, Nikita
, Selzner, Markus
, Minkovich, Michelle
, Famure, Olusegun
, Ghanekar, Anand
, Li, Yanhong
, Lee, Jason Y.
, Liu, Michelle
, Kim, S. Joseph
in
Abscesses
/ Adult
/ Aged
/ Analysis
/ Candidates
/ Chronic kidney failure
/ Clinical outcomes
/ Complications and side effects
/ Female
/ Graft Survival
/ Grafting
/ Hematoma
/ Hemoglobin
/ Hospitals
/ Humans
/ Internal Medicine
/ Kidney
/ Kidney Failure, Chronic - surgery
/ Kidney Transplantation
/ Kidney Transplantation - adverse effects
/ Kidney transplants
/ Kidneys
/ Male
/ Medical research
/ Medicine
/ Medicine & Public Health
/ Medicine, Experimental
/ Middle Aged
/ Observational studies
/ Patient outcomes
/ Patient Readmission - statistics & numerical data
/ Patients
/ Postoperative Complications - epidemiology
/ Postoperative Complications - etiology
/ Retrospective Studies
/ Sensitivity analysis
/ Statistical models
/ Surgery
/ Surgical complications
/ Surgical site infections
/ Thrombosis
/ Time Factors
/ Transplantation
/ Treatment Outcome
/ Ultrasonic imaging
/ Variables
/ Veins & arteries
/ Wound dehiscence
2024
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Impact of early surgical complications on kidney transplant outcomes
Journal Article
Impact of early surgical complications on kidney transplant outcomes
2024
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Overview
Background
Kidney transplantation (KT) improves clinical outcomes of patients with end stage renal disease. Little has been reported on the impact of early post-operative surgical complications (SC) on long-term clinical outcomes following KT. We sought to determine the impact of vascular complications, urological complications, surgical site complications, and peri-graft collections within 30 days of transplantation on patient survival, graft function, and hospital readmissions.
Methods
We conducted a single-centre, observational cohort study examining adult patients (≥ 18 years) who received a kidney transplant from living and deceased donors between January 1st, 2005 and December 31st, 2015 with follow-up until December 31
st
, 2016 (
n
= 1,334). Univariable and multivariable analyses were performed with Cox proportional hazards models to analyze the outcomes of SC in the early post-operative period after KT.
Results
The cumulative probability of SC within 30 days of transplant was 25%, the most common SC being peri-graft collections (66.8%). Multivariable analyses showed significant relationships between Clavien Grade 1 SC and death with graft function (HR 1.78 [95% CI: 1.11, 2.86]), and between Clavien Grades 3 to 4 and hospital readmissions (HR 1.95 [95% CI: 1.37, 2.77]).
Conclusions
Early SC following KT are common and have a significant influence on long-term patient outcomes.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Adult
/ Aged
/ Analysis
/ Complications and side effects
/ Female
/ Grafting
/ Hematoma
/ Humans
/ Kidney
/ Kidney Failure, Chronic - surgery
/ Kidney Transplantation - adverse effects
/ Kidneys
/ Male
/ Medicine
/ Patient Readmission - statistics & numerical data
/ Patients
/ Postoperative Complications - epidemiology
/ Postoperative Complications - etiology
/ Surgery
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