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Isabl Platform, a digital biobank for processing multimodal patient data
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Isabl Platform, a digital biobank for processing multimodal patient data
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Journal Article
Isabl Platform, a digital biobank for processing multimodal patient data
2020
Overview
Background
The widespread adoption of high throughput technologies has democratized data generation. However, data processing in accordance with best practices remains challenging and the data capital often becomes siloed. This presents an opportunity to consolidate data assets into digital biobanks—ecosystems of readily accessible, structured, and annotated datasets that can be dynamically queried and analysed.
Results
We present Isabl, a customizable plug-and-play platform for the processing of multimodal patient-centric data. Isabl's architecture consists of a relational database (Isabl DB), a command line client (Isabl CLI), a RESTful API (Isabl API) and a frontend web application (Isabl Web). Isabl supports automated deployment of user-validated pipelines across the entire data capital. A full audit trail is maintained to secure data provenance, governance and ensuring reproducibility of findings.
Conclusions
As a digital biobank, Isabl supports continuous data utilization and automated meta analyses at scale, and serves as a catalyst for research innovation, new discoveries, and clinical translation.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Analysis information management system
/ Biomedical and Life Sciences
/ Computational Biology/Bioinformatics
/ Computer Appl. in Life Sciences
/ Genomics
/ Humans
/ Internet
/ Methods
/ Multimodal user interfaces (Computers)
/ Novel computational methods for analysis of biological systems
/ Ontology
/ Software
