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mode of antifungal action of plant, insect and human defensins

by Aerts, A. M , Thevissen, K , Cammue, B. P. A , François, I. E. J. A

in Amino Acid Sequence / Animals / Antifungal activity / Antifungal Agents - chemistry / Antifungal Agents - immunology / Antifungal Agents - metabolism / Antimicrobial peptides / Biochemistry / Biomedical and Life Sciences / Biomedicine / Cell Biology / defensin / Defensins / Defensins - chemistry / Defensins - genetics / Defensins - immunology / Defensins - metabolism / Flowers & plants / Fungi / Fungicides / Host-Pathogen Interactions - immunology / Humans / Immune system / Immunity, Innate / Innate immunity / Insect Proteins - immunology / Insect Proteins - metabolism / Insects / Life Sciences / Microbiology / Microorganisms / Mode of antifungal action / Models, Molecular / Molecular Sequence Data / Pathology / Peptides / plant / Plant Proteins - chemistry / Plant Proteins - genetics / Plant Proteins - immunology / Plant Proteins - metabolism / Review / Virulence

2008

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mode of antifungal action of plant, insect and human defensins

by Aerts, A. M , Thevissen, K , Cammue, B. P. A , François, I. E. J. A

2008

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mode of antifungal action of plant, insect and human defensins

by Aerts, A. M , Thevissen, K , Cammue, B. P. A , François, I. E. J. A

2008

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Journal Article

mode of antifungal action of plant, insect and human defensins

Aerts, A. M,

Thevissen, K,

Cammue, B. P. A,

François, I. E. J. A

2008

Overview

Defensins are small (~ 5 kDa), basic, cysteine-rich antimicrobial peptides that fulfill an important role in the innate immunity of their host by combating pathogenic invading micro-organisms. Defensins can inhibit the growth or virulence of microorganisms directly or can do so indirectly by enhancing the host's immune system. Because of their wide distribution in nature, defensins are believed to be ancient molecules with a common ancestor that arose more than a billion years ago. This review summarizes current knowledge concerning the mode of antifungal action of plant, insect and human defensins.

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Publisher

Basel : SP Birkhäuser Verlag Basel,SP Birkhäuser Verlag Basel,Springer Nature B.V

Subject

Amino Acid Sequence

/ Animals

/ Antifungal activity

/ Antifungal Agents - chemistry

/ Antifungal Agents - immunology

/ Antifungal Agents - metabolism

/ Antimicrobial peptides