Journal Article

Cognitive decline as the main manifestation of diabetic striatal disease but without involuntary movements: a case report

Li, He, Tang, Wei, Cheng, YiRan, Wu, Tong, Hu, YiBin, Jia, GeHui, Wang, KangFeng

2023

Overview

Diabetic striatopathy (DS) is a rare central nervous system complication of diabetes mellitus, characterized mainly by non-ketotic hyperglycemia and lateralized involuntary movements. Patients with diabetic striatopathy manifested solely by subacute cognitive decline were rarely reported. In this paper, we report a patient with DS who presented solely with subacute cognitive decline without involuntary movements, and cranial CT showed bilateral high density in the basal ganglia. In contrast, SWI showed microhemorrhages in the right caudate nucleus head. After one week of treatment, including glycemic control, the patient showed significant improvement in cognitive function, while a repeat cranial CT showed improved hyperdensity in the right basal ganglia region. 1 month later, at telephone follow-up, the patient’s symptoms did not recur.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Basal ganglia / Blood tests / Brain diseases / Brain research / Calcification / Care and treatment / Case Report / Case reports / Caudate nucleus / Causes of / Central nervous system / Chorea / Clinical medicine / Cognition disorders / Cognitive ability / Complications and side effects / Consciousness / Corpus striatum / Diabetes / Diabetes mellitus / Diabetes non ketotic hemichorea / Diabetes therapy / Diabetic neuropathies / Diabetic Striatopathy / Diabetics / Diagnosis / Disease / Drugs / Encephalitis / Glucose / Health aspects / Hemoglobin / Hyperglycemia / Hyperlipidemia / Magnetic resonance imaging / Medicine / Medicine & Public Health / Memory / Neostriatum / Neurochemistry / Neurology / Neurosurgery / Patients / Skull / Subacute cognitive decline / Type 2 diabetes