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A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder
A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder
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A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder
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A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder
A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder
Journal Article

A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder

2010
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Overview
Tobacco smoking is more prevalent among people with mental illnesses, including bipolar disorder, than in the general community. Most data are cross-sectional, and there are no prospective trials examining the relationship of smoking to outcome in bipolar disorder. The impact of tobacco smoking on mental health outcomes was investigated in a 24-month, naturalistic, longitudinal study of 240 people with bipolar disorder or schizoaffective disorder. Participants were interviewed and data recorded by trained study clinicians at 9 interviews during the study period. Comparisons were made between participants who smoked daily (n = 122) and the remaining study participants (n = 117). During the 24-month study period, the daily smokers had poorer scores on the Clinical Global Impressions–Depression ( P = .034) and Clinical Global Impressions–Overall Bipolar ( P = .026) scales and had lengthier stays in hospital ( P = .012), compared with nonsmokers. Smoking status was determined by self-report. Nicotine dependence was not measured. These findings suggest that smoking is associated with poorer mental health outcomes in bipolar and schizoaffective disorder.