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Outcome of carcinoid heart syndrome in patients enrolled in the SwissNet cohort
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Outcome of carcinoid heart syndrome in patients enrolled in the SwissNet cohort
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Outcome of carcinoid heart syndrome in patients enrolled in the SwissNet cohort
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Journal Article
Outcome of carcinoid heart syndrome in patients enrolled in the SwissNet cohort
2023
Overview
Background
Carcinoid heart disease is a rare disease which develops in patients with functional neuroendocrine tumors in an advanced tumor state. Patients diagnosed with carcinoid heart disease have a poor longtime prognosis with respect to morbidity and mortality and long-term data on patient outcomes are lacking.
Methods and results
In this retrospective study, we analyzed outcomes of 23 patients with carcinoid heart disease enrolled into the SwissNet database. We observed that early diagnosis with echocardiographic surveillance of carcinoid heart disease during the course of the neuroendocrine tumor disease was beneficial to overall survival of patients.
Conclusion
Through nationwide patient enrollment, the SwissNet registry is a powerful data tool to identify, follow-up and evaluate long-term patient outcomes in patients with rare neuroendocrine tumor driven pathologies including carcinoid heart syndrome with observational methods enabling better therapy optimization to improve patient`s long-term perspectives and survival. In line with the current ESMO recommendations, our data proposes that heart echocardiography should be included as part of the general physical assessment in patients with newly diagnosed NET.
Highlights
CHD is associated with poor prognosis
Early CHD detection prolongs survival
Echo as baseline prior NET therapy is recommended
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
