Asset Details
Do you wish to reserve the book?
The biophysics and cell biology of lipid droplets
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
The biophysics and cell biology of lipid droplets
Do you wish to request the book?
The biophysics and cell biology of lipid droplets
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
The biophysics and cell biology of lipid droplets
2013
Overview
Key Points
Cellular lipid droplets store lipids as reservoirs for metabolic energy and membrane precursors.
Lipid droplets form the dispersed phase of a cellular emulsion in the aqueous cytosol.
Principles of emulsion science are applicable to many lipid droplet-related processes.
Emulsions properties, such as lipid droplet size, are governed by surface properties of the phase interface.
Different lipids and proteins can modulate lipid droplet surface properties and hence lipid droplet biology.
Lipid droplets are intracellular organelles that store oil-based reserves of metabolic energy and components of membrane lipids. Basic biophysical principles of emulsions are important for lipid droplet biology, their formation, growth and shrinkage. Such mechanisms enable cells to use emulsified oil when required. The surfactant composition at the lipid droplet surface is crucial for homeostasis and protein targeting to their surfaces.
Lipid droplets are intracellular organelles that are found in most cells, where they have fundamental roles in metabolism. They function prominently in storing oil-based reserves of metabolic energy and components of membrane lipids. Lipid droplets are the dispersed phase of an oil-in-water emulsion in the aqueous cytosol of cells, and the importance of basic biophysical principles of emulsions for lipid droplet biology is now being appreciated. Because of their unique architecture, with an interface between the dispersed oil phase and the aqueous cytosol, specific mechanisms underlie their formation, growth and shrinkage. Such mechanisms enable cells to use emulsified oil when the demands for metabolic energy or membrane synthesis change. The regulation of the composition of the phospholipid surfactants at the surface of lipid droplets is crucial for lipid droplet homeostasis and protein targeting to their surfaces.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
