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The precursors of memory: models and controversies
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The precursors of memory: models and controversies
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Journal Article
The precursors of memory: models and controversies
2009
Overview
Understanding how memory T cells develop has important implications for vaccine design. Here,
Nature Reviews Immunology
asks four leading researchers in this field their thoughts on the ontogeny and lineage relationships of memory T cells.
The adaptive immune system has evolved a unique capacity to remember a pathogen through the generation of memory T cells, which rapidly protect the host in the event of reinfection. How memory T cells develop and the relationship between effector and memory T cells has been actively debated in the literature for many years and several models have been proposed to explain the divergent developmental fates of T cell progeny. Here,
Nature Reviews Immunology
asks four leading researchers in the field to provide their thoughts and opinions on the ontogeny of memory T cells and its implications for vaccine design.
Publisher
Nature Publishing Group UK,Nature Publishing Group
