Journal Article

Design and Physical Properties of 3-Dimensional Printed Models Used for Neurointervention: A Systematic Review of the Literature

Gutierrez, Liza C, Levy, Elad I, Ducharme, Richard W, Snyder, Kenneth V, Davies, Jason M, Ionita, Ciprian N, Waqas, Muhammad, Siddiqui, Adnan H, Springer, Michael E, Mokin, Maxim, Lim, Jaims, Vakharia, Kunal, Meess, Karen M, Nagesh, Swetadri Vasan Setlur

2020

Overview

Abstract Background Three-dimensional (3D) printing has revolutionized training, education, and device testing. Understanding the design and physical properties of 3D-printed models is important. Objective To systematically review the design, physical properties, accuracy, and experimental outcomes of 3D-printed vascular models used in neurointervention. Methods We conducted a systematic review of the literature between January 1, 2000 and September 30, 2018. Public/Publisher MEDLINE (PubMed), Web of Science, Compendex, Cochrane, and Inspec databases were searched using Medical Subject Heading terms for design and physical attributes of 3D-printed models for neurointervention. Information on design and physical properties like compliance, lubricity, flow system, accuracy, and outcome measures were collected. Results A total of 23 articles were included. Nine studies described 3D-printed models for stroke intervention. Tango Plus (Stratasys) was the most common material used to develop these models. Four studies described a population-representative geometry model. All other studies reported patient-specific vascular geometry. Eight studies reported complete reconstruction of the circle of Willis, anterior, and posterior circulation. Four studies reported a model with extracranial vasculature. One prototype study reported compliance and lubricity. Reported circulation systems included manual flushing, programmable pistons, peristaltic, and pulsatile pumps. Outcomes included thrombolysis in cerebral infarction, post-thrombectomy flow restoration, surgical performance, and qualitative feedback. Conclusion Variations exist in the material, design, and extent of reconstruction of vasculature of 3D-printed models. There is a need for objective characterization of 3D-printed vascular models. We propose the development of population representative 3D-printed models for skill improvement or device testing.

• Publisher: Oxford University Press,Copyright by the Congress of Neurological Surgeons,Wolters Kluwer Health, Inc
• Subject: 3-D printers / Accuracy / Aneurysms / Education / Friction / Geometry / Humans / Medical research / Medicine, Experimental / Models, Anatomic / Neurosurgery / Neurosurgical Procedures - methods / Neurosurgical Procedures - trends / Physical properties / Printing, Three-Dimensional - trends / Prostheses and Implants - trends / Prosthesis Design - methods / Prosthesis Design - trends / Review / Stroke / Systematic review / Thrombolytic drugs