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Rationale and design for cognitive behavioral therapy for anxiety disorders in children with autism spectrum disorder: a study protocol of a randomized controlled trial
by
Thomsen, Per Hove
, Sørensen, Merete Juul
, Kilburn, Tina R.
, Thastum, Mikael
, Rask, Charlotte Ulrikka
, Arendt, Kristian Bech
, Rapee, Ronald M.
in
Adaptation
/ Adolescent
/ Adolescent Behavior
/ Age Factors
/ Analysis
/ Anxiety disorders
/ Anxiety Disorders - diagnosis
/ Anxiety Disorders - psychology
/ Anxiety Disorders - therapy
/ Anxiety in children
/ Attention deficit hyperactivity disorder
/ Autism
/ Autism spectrum disorder
/ Autism Spectrum Disorder - diagnosis
/ Autism Spectrum Disorder - psychology
/ Autism Spectrum Disorder - therapy
/ Behavior modification
/ Biomedicine
/ Care and treatment
/ Child
/ Child & adolescent psychiatry
/ Child Behavior
/ Children
/ Children & youth
/ Clinical trials
/ Cognitive Behavioral Therapy
/ Cognitive therapy
/ Comorbidity
/ Counseling
/ Denmark
/ Diagnosis
/ Families & family life
/ Female
/ Health aspects
/ Health Sciences
/ Hospitals
/ Humans
/ Interdisciplinary aspects
/ Male
/ Manuals as Topic
/ Medicine
/ Medicine & Public Health
/ Mental disorders
/ Mental Health
/ Multidisciplinary teams
/ Obsessive compulsive disorder
/ Parents & parenting
/ Pervasive developmental disorders
/ Prospective Studies
/ Quality of life
/ Randomized Controlled Trials as Topic
/ Social aspects
/ Statistics for Life Sciences
/ Study Protocol
/ Teenagers
/ Time Factors
/ Treatment Outcome
2018
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Rationale and design for cognitive behavioral therapy for anxiety disorders in children with autism spectrum disorder: a study protocol of a randomized controlled trial
by
Thomsen, Per Hove
, Sørensen, Merete Juul
, Kilburn, Tina R.
, Thastum, Mikael
, Rask, Charlotte Ulrikka
, Arendt, Kristian Bech
, Rapee, Ronald M.
in
Adaptation
/ Adolescent
/ Adolescent Behavior
/ Age Factors
/ Analysis
/ Anxiety disorders
/ Anxiety Disorders - diagnosis
/ Anxiety Disorders - psychology
/ Anxiety Disorders - therapy
/ Anxiety in children
/ Attention deficit hyperactivity disorder
/ Autism
/ Autism spectrum disorder
/ Autism Spectrum Disorder - diagnosis
/ Autism Spectrum Disorder - psychology
/ Autism Spectrum Disorder - therapy
/ Behavior modification
/ Biomedicine
/ Care and treatment
/ Child
/ Child & adolescent psychiatry
/ Child Behavior
/ Children
/ Children & youth
/ Clinical trials
/ Cognitive Behavioral Therapy
/ Cognitive therapy
/ Comorbidity
/ Counseling
/ Denmark
/ Diagnosis
/ Families & family life
/ Female
/ Health aspects
/ Health Sciences
/ Hospitals
/ Humans
/ Interdisciplinary aspects
/ Male
/ Manuals as Topic
/ Medicine
/ Medicine & Public Health
/ Mental disorders
/ Mental Health
/ Multidisciplinary teams
/ Obsessive compulsive disorder
/ Parents & parenting
/ Pervasive developmental disorders
/ Prospective Studies
/ Quality of life
/ Randomized Controlled Trials as Topic
/ Social aspects
/ Statistics for Life Sciences
/ Study Protocol
/ Teenagers
/ Time Factors
/ Treatment Outcome
2018
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Rationale and design for cognitive behavioral therapy for anxiety disorders in children with autism spectrum disorder: a study protocol of a randomized controlled trial
by
Thomsen, Per Hove
, Sørensen, Merete Juul
, Kilburn, Tina R.
, Thastum, Mikael
, Rask, Charlotte Ulrikka
, Arendt, Kristian Bech
, Rapee, Ronald M.
in
Adaptation
/ Adolescent
/ Adolescent Behavior
/ Age Factors
/ Analysis
/ Anxiety disorders
/ Anxiety Disorders - diagnosis
/ Anxiety Disorders - psychology
/ Anxiety Disorders - therapy
/ Anxiety in children
/ Attention deficit hyperactivity disorder
/ Autism
/ Autism spectrum disorder
/ Autism Spectrum Disorder - diagnosis
/ Autism Spectrum Disorder - psychology
/ Autism Spectrum Disorder - therapy
/ Behavior modification
/ Biomedicine
/ Care and treatment
/ Child
/ Child & adolescent psychiatry
/ Child Behavior
/ Children
/ Children & youth
/ Clinical trials
/ Cognitive Behavioral Therapy
/ Cognitive therapy
/ Comorbidity
/ Counseling
/ Denmark
/ Diagnosis
/ Families & family life
/ Female
/ Health aspects
/ Health Sciences
/ Hospitals
/ Humans
/ Interdisciplinary aspects
/ Male
/ Manuals as Topic
/ Medicine
/ Medicine & Public Health
/ Mental disorders
/ Mental Health
/ Multidisciplinary teams
/ Obsessive compulsive disorder
/ Parents & parenting
/ Pervasive developmental disorders
/ Prospective Studies
/ Quality of life
/ Randomized Controlled Trials as Topic
/ Social aspects
/ Statistics for Life Sciences
/ Study Protocol
/ Teenagers
/ Time Factors
/ Treatment Outcome
2018
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Rationale and design for cognitive behavioral therapy for anxiety disorders in children with autism spectrum disorder: a study protocol of a randomized controlled trial
Journal Article
Rationale and design for cognitive behavioral therapy for anxiety disorders in children with autism spectrum disorder: a study protocol of a randomized controlled trial
2018
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Overview
Background
Autism spectrum disorder (ASD) is found in approximately 1% of the population and includes core symptoms that affect general and social development. Beside these core symptoms, it is suggested that up to 60% of children with ASD suffer from comorbid anxiety disorders which may further affect educational, social and general development as well as quality of life. The main goal of this study is to examine the effectiveness of a manualized cognitive behavioral therapy (CBT) anxiety program adapted for children with ASD.
Methods
This study is a randomized controlled trial (RCT). Fifty children with ASD and anxiety, aged 7 to 13 years, will be randomly assigned to group CBT or a wait-list control (WL) condition. The design will follow a two (CBT and WL) by two (pre–post assessment) mixed between–within design. The control group will receive intervention after the waitlist period of 13 weeks. Primary outcomes are diagnostic status and severity of the anxiety disorders, measured with The Anxiety Disorder Interview Schedule for DSM-IV, Parent and Child Versions. Secondary outcomes are parent and child ratings on questionnaires on the child’s level of anxiety and impact on everyday life. Additional outcomes entail information gathered from parents, child and teachers on the child’s behavior and negative self-statements, together with social and adaptive skills. Follow-up data will be collected 3 months after intervention.
Discussion
This study aims to evaluate the effectiveness of a manualized CBT program in Danish children with ASD and anxiety within a mental health clinic setting. The hypothesis is that training anxiety reduction skills will decrease anxiety in children, as well as ensure better psychosocial development for the child in general.
Trial registration
https://ClinicalTrials.gov (
NCT02908321
). Registered 19th of September 2016.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Analysis
/ Anxiety Disorders - diagnosis
/ Anxiety Disorders - psychology
/ Attention deficit hyperactivity disorder
/ Autism
/ Autism Spectrum Disorder - diagnosis
/ Autism Spectrum Disorder - psychology
/ Autism Spectrum Disorder - therapy
/ Child
/ Child & adolescent psychiatry
/ Children
/ Cognitive Behavioral Therapy
/ Denmark
/ Female
/ Humans
/ Male
/ Medicine
/ Obsessive compulsive disorder
/ Pervasive developmental disorders
/ Randomized Controlled Trials as Topic
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