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A novel approach to immune thrombocytopenia intervention: modulating intestinal homeostasis
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A novel approach to immune thrombocytopenia intervention: modulating intestinal homeostasis
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Journal Article
A novel approach to immune thrombocytopenia intervention: modulating intestinal homeostasis
2024
Overview
Immune thrombocytopenia (ITP) is a prevalent hemorrhage condition that causes notable immune-related abnormalities. Recently discovered data has shown that the intestinal flora plays a crucial role in maintaining a balanced immune system. Furthermore, an imbalance in gut flora has the potential to increase the possibility of developing ITP. Moreover, some studies reported a strong link between inflammatory bowel disease (IBD) and ITP. In this review, we described the significance of gut immunity in ITP. In addition, we explored the associations between gut flora and ITP as well as IBD and ITP. Finally, we examined the effectiveness of existing therapies that regulate gut homeostasis and their impact on the prognosis of patients with ITP.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Animals
/ B cells
/ Bacteria
/ Biomedical and Life Sciences
/ Cytokines and Growth Factors
/ Feces
/ Gastrointestinal Microbiome - immunology
/ Humans
/ Idiopathic thrombocytopenic purpura
/ Inflammatory Bowel Diseases - immunology
/ Innate immunity and inflammation
/ Microbiota (Symbiotic organisms)
/ Purpura, Thrombocytopenic, Idiopathic - immunology
/ Review
/ Vaccine
