Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Damage-associated molecular patterns in cancer: a double-edged sword

by Hernandez, C , Huebener, P , Schwabe, R F

in 631/250/256 / 631/67/580/1884 / 631/80/82 / Alarmins - genetics / Alarmins - metabolism / Animals / Apoptosis / Carcinogenesis / Cell Biology / Cell death / Cell Death - genetics / Cell Death - immunology / Cell Transformation, Neoplastic - genetics / Cell Transformation, Neoplastic - immunology / Cell Transformation, Neoplastic - metabolism / Cytotoxicity / Disease Progression / Gene expression / Genetic aspects / Genotypes / Health aspects / Human Genetics / Humans / Immune system / Immunogenicity / Immunomodulation - genetics / Inflammation / Inflammation - complications / Inflammation - genetics / Inflammation - immunology / Inflammation - metabolism / Internal Medicine / Medicine / Medicine & Public Health / Molecular biology / Neoplasms - etiology / Neoplasms - metabolism / Neoplasms - pathology / Neoplasms - therapy / Oncology / review / Stress, Physiological - genetics / Stress, Physiological - immunology / Tumor cells / Tumorigenesis

2016

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Damage-associated molecular patterns in cancer: a double-edged sword

by Hernandez, C , Huebener, P , Schwabe, R F

2016

Confirm

Do you wish to request the book?

Damage-associated molecular patterns in cancer: a double-edged sword

by Hernandez, C , Huebener, P , Schwabe, R F

2016

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Damage-associated molecular patterns in cancer: a double-edged sword

Hernandez, C,

Huebener, P,

Schwabe, R F

2016

Overview

Damage-associated molecular patterns (DAMPs) are released in response to cell death and stress, and are potent triggers of sterile inflammation. Recent evidence suggests that DAMPs may also have a key role in the development of cancer, as well as in the host response to cytotoxic anti-tumor therapy. As such, DAMPs may exert protective functions by alerting the immune system to the presence of dying tumor cells, thereby triggering immunogenic tumor cell death. On the other hand, cell death and release of DAMPs may also trigger chronic inflammation and, thereby promote the development or progression of tumors. Here, we will review the contribution of candidate DAMPs and their receptors, and discuss the evidence for DAMPs as tumor-promoting and anti-tumor effectors, as well as unsolved questions such as DAMP release from non-tumor cells as well as the existence of tumor-specific DAMPs.

Share this book

Add to My Shelf

Publisher

Nature Publishing Group UK,Nature Publishing Group

Subject

631/250/256

/ 631/67/580/1884

/ 631/80/82

/ Alarmins - genetics

/ Alarmins - metabolism

/ Animals

/ Apoptosis