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Depression in adolescence
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Depression in adolescence
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Depression in adolescence
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Journal Article
Depression in adolescence
2012
Overview
Unipolar depressive disorder in adolescence is common worldwide but often unrecognised. The incidence, notably in girls, rises sharply after puberty and, by the end of adolescence, the 1 year prevalence rate exceeds 4%. The burden is highest in low-income and middle-income countries. Depression is associated with substantial present and future morbidity, and heightens suicide risk. The strongest risk factors for depression in adolescents are a family history of depression and exposure to psychosocial stress. Inherited risks, developmental factors, sex hormones, and psychosocial adversity interact to increase risk through hormonal factors and associated perturbed neural pathways. Although many similarities between depression in adolescence and depression in adulthood exist, in adolescents the use of antidepressants is of concern and opinions about clinical management are divided. Effective treatments are available, but choices are dependent on depression severity and available resources. Prevention strategies targeted at high-risk groups are promising.
Publisher
Elsevier Ltd,Elsevier,Elsevier Limited
Subject
/ Adult and adolescent clinical studies
/ Biological and medical sciences
/ Depressive Disorder - diagnosis
/ Depressive Disorder - epidemiology
/ Depressive Disorder - genetics
/ Depressive Disorder - therapy
/ Female
/ Genetics
/ girls
/ Hormones
/ Humans
/ Male
/ Psychology. Psychoanalysis. Psychiatry
/ puberty
/ Stress
/ Studies
/ Suicide
/ United Kingdom - epidemiology
