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Extra-urogenital infection by Mycoplasma hominis in transplant patients: two case reports and literature review
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Extra-urogenital infection by Mycoplasma hominis in transplant patients: two case reports and literature review
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Journal Article
Extra-urogenital infection by Mycoplasma hominis in transplant patients: two case reports and literature review
2023
Overview
Background
Mycoplasma hominis
is a facultative anaerobic bacterium commonly present in the urogenital tract. In recent years,
M. hominis
has increasingly been associated with extra-urogenital tract infections, particularly in immunosuppressed patients. Detecting
M. hominis
in a diagnostic laboratory can be challenging due to its slow growth rate, absence of a cell wall, and the requirements of specialized media and conditions for optimal growth. Consequently, it is necessary to establish guidelines for the detection of this microorganism and to request the appropriate microbiological work-up of immunosuppressed patients.
Case Presentation
We hereby present two cases of solid organ transplant patients who developed
M. hominis
infection. Microscopic examination of the bronchial lavage and pleural fluid showed no microorganisms. However, upon inoculating the specimens onto routine microbiology media, the organism was successfully identified and confirmation was performed using 16S rDNA sequencing. Both patients received appropriate treatment resulting in the resolution of
M. hominis
infection.
Conclusions
The prompt detection of
M. hominis
in a clinical specimen can have a significant impact on patient care by allowing for early intervention and ultimately resulting in more favorable clinical outcomes, especially in transplant patients.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
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