Journal Article

Correction of respiratory artifacts in MRI head motion estimates

Fair, Damien A., van der Kouwe, Andre, Garavan, Hugh, Laumann, Timothy O., Gratton, Caterina, Feldstein-Ewing, Sarah W., Earl, Eric A., Dosenbach, Nico U.F., Perrone, Anders, Klein, Rachel L., Mirro, Amy E., Hampton, Jacqueline M., Petersen, Steven E., Adeyemo, Babatunde, Watts, Richard, Van, Andrew N., Schlaggar, Bradley L., Nigg, Joel T., Feczko, Eric, Koller, Jonathan M., Miranda-Dominguez, Oscar, Barch, Deanna M., Snyder, Abraham Z., Dale, Anders M., Tisdall, M. Dylan, Nagel, Bonnie J., Greene, Deanna J., Hagler, Donald J.

2020

Overview

Head motion represents one of the greatest technical obstacles in magnetic resonance imaging (MRI) of the human brain. Accurate detection of artifacts induced by head motion requires precise estimation of movement. However, head motion estimates may be corrupted by artifacts due to magnetic main field fluctuations generated by body motion. In the current report, we examine head motion estimation in multiband resting state functional connectivity MRI (rs-fcMRI) data from the Adolescent Brain and Cognitive Development (ABCD) Study and comparison ‘single-shot’ datasets. We show that respirations contaminate movement estimates in functional MRI and that respiration generates apparent head motion not associated with functional MRI quality reductions. We have developed a novel approach using a band-stop filter that accurately removes these respiratory effects from motion estimates. Subsequently, we demonstrate that utilizing a band-stop filter improves post-processing fMRI data quality. Lastly, we demonstrate the real-time implementation of motion estimate filtering in our FIRMM (Framewise Integrated Real-Time MRI Monitoring) software package. •Respiratory perturbations of the main field inflate fMRI head motion estimates.•Breathing-related head motion artifacts compromise functional connectivity quality.•Notch filtering motion estimates (respiratory frequency band) improves data quality.•Motion estimate filtering can be achieved in real-time with FIRMM software.

• Publisher: Elsevier Inc,Elsevier Limited,Elsevier
• Subject: Adolescent / Brain mapping / Brain research / Child / Cognitive ability / Cognitive development / Female / Functional magnetic resonance imaging / Functional Neuroimaging - standards / Head / Head Movements / Humans / Magnetic fields / Magnetic resonance imaging / Magnetic Resonance Imaging - standards / Male / Neural networks / Neuroimaging / Respiration / Scanners