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Neurosyphilis presenting as hypomania
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Journal Article
Neurosyphilis presenting as hypomania
2021
Overview
The rate of syphilis in Canada has been increasing in the last decade. Outbreaks often disproportionately affect men who have sex with men, though outbreaks among heterosexual people have been documented in recent years in both urban and rural areas. Neurosyphilis presents more frequently in people with concurrent HIV infection, particularly those with CD4 T-cell counts < 350 cells/μL (0.35 x 109/L). According to retrospective studies, 40% of patients have ocular involvement, including uveitis, retinal pathology and vision loss. A third of patients have cognitive impairment and a third have neurologic manifestations, such as headache, aphasia, auditory hallucinations and stroke. Psychiatric symptoms vary widely, when they occur. Hypomania is uncommon, affecting fewer than 10% of people with neurosyphilis Neurological sequela are often permanent, but our patient made a full recovery after outpatient treatment with intravenous penicillin. Here, Jeon and Gough examine the case of 60-year-old man with neurosyphilis.
Publisher
Elsevier Inc,CMA Joule Inc,CMA Impact, Inc
