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The unique characteristics of COVID-19 coagulopathy
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The unique characteristics of COVID-19 coagulopathy
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Journal Article
The unique characteristics of COVID-19 coagulopathy
2020
Overview
Thrombotic complications and coagulopathy frequently occur in COVID-19. However, the characteristics of COVID-19-associated coagulopathy (CAC) are distinct from those seen with bacterial sepsis-induced coagulopathy (SIC) and disseminated intravascular coagulation (DIC), with CAC usually showing increased D-dimer and fibrinogen levels but initially minimal abnormalities in prothrombin time and platelet count. Venous thromboembolism and arterial thrombosis are more frequent in CAC compared to SIC/DIC. Clinical and laboratory features of CAC overlap somewhat with a hemophagocytic syndrome, antiphospholipid syndrome, and thrombotic microangiopathy. We summarize the key characteristics of representative coagulopathies, discussing similarities and differences so as to define the unique character of CAC.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Blood Coagulation Disorders - blood
/ Blood Coagulation Disorders - diagnosis
/ Blood Coagulation Disorders - epidemiology
/ Blood Coagulation Tests - methods
/ Coronavirus Infections - blood
/ Coronavirus Infections - diagnosis
/ Coronavirus Infections - epidemiology
/ COVID-19
/ Disseminated intravascular coagulation
/ Fibrin
/ Humans
/ Inflammation Mediators - blood
/ Medicine
/ Platelet Aggregation - physiology
/ Pneumonia, Viral - diagnosis
/ Pneumonia, Viral - epidemiology
/ Review
/ Sepsis
