Journal Article

Long-term relative survival of patients with gastric cancer from a large-scale cohort: a period-analysis

Liu, Hao, Yang, Weihao, Zhang, Hengyi, Tan, Xin, Li, Guoxin, Zhao, Liying, He, Wenjun

2024

Overview

Background Gastric cancer poses a significant global health challenge. We aim to use period analysis to assess the changes in gastric cancer treatment at our center over the past 15 years. This study reflects the current state of gastric cancer treatment at our center and provides valuable data to support clinical advancements. Method We used period analysis to evaluate the survival status of 3915 patients with gastric cancer at Nanfang Hospital, Southern Medical University, over a 15-year period spaning from 2008 to 2022. The 5-year relative survival rates were analyzed. Result Our findings indicate that the 5-year relative survival rate at our center from 2018 to 2022 is 71.4%. From 2018 to 2022, the 5-year relative survival rates for patients aged < 40, 40–54, 55–69, and ≥ 70 reached 67.5%, 73.5%, 72.0%, and 67.1%, respectively. For stage IV patients, the 5-year relative survival rate reached 29% in 2018–2022. For stage I-III patients, the 5-year relative survival rate reached 89.7% in 2018–2022. The five-year relative survival rate for patients who underwent laparoscopic surgery at our center rose from 50.3% in 2008–2012 to 71.4% in 2018–2022. Overall, there has been a notable increase in the 5-year relative survival rates, regardless of age, gender, region, or tumor stage. Conclusion Period analysis over the past 15 years shows significant improvement in the 5-year survival rate for gastric cancer at our center. This progress is due to standardized surgical techniques, perioperative management, and immunotherapy, providing robust data for evaluating the efficacy of recent treatments.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: 5-year relative survival / Adult / Aged / Analysis / Biomedical and Life Sciences / Biomedicine / Cancer / Cancer patients / Cancer Research / Cancer surgery / Cancer therapies / Care and treatment / Chemotherapy / Cohort Studies / Demographic aspects / Diagnosis / Dissection / Event history analysis / Female / Gastrectomy - mortality / Gastric cancer / Global health / Health aspects / Health Promotion and Disease Prevention / Hospitals / Humans / Immunotherapy / Laparoscopic surgery / Laparoscopy / Lymphatic system / Male / Medical colleges / Medical prognosis / Medical research / Medicine/Public Health / Methods / Middle Aged / Mortality / Neoplasm Staging / Oncology / Oncology, Experimental / Patient compliance / Patient outcomes / Patients / Period analysis / Public health / Retrospective Studies / Stomach cancer / Stomach Neoplasms - mortality / Stomach Neoplasms - pathology / Stomach Neoplasms - therapy / Surgical Oncology / Survival / Survival analysis / Survival Rate / Trends