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Long non-coding RNAs regulate drug resistance in cancer
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Journal Article
Long non-coding RNAs regulate drug resistance in cancer
2020
Overview
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various mechanisms. Over the last decade, it has been reported that 1ong noncoding RNAs (lncRNAs) can mediate carcinogenesis and drug resistance/sensitivity in cancer cells. This article reviews, in detail, recent studies regarding the roles of lncRNAs in mediating drug resistance.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Biomarkers, Tumor - genetics
/ Biomedical and Life Sciences
/ Cancer
/ Carcinogenesis - drug effects
/ DNA
/ Drug Resistance, Neoplasm - genetics
/ Enzymes
/ Gene Expression Regulation, Neoplastic
/ Genomes
/ Humans
/ Kinases
/ Low density lipoprotein receptors
/ Non-coding RNAs and RNA modifiers in cancer progression and cancer cells resistance to therapies
/ Oncology
/ Proteins
/ Review
/ RNA, Long Noncoding - genetics
/ Surgery
/ Tumors
